Posture Dependent Hypoxia Following Lobectomy: The Achilles Tendon of the Lung Surgeon?

: Platypnoea-Orthodeoxia Syndrome is an uncommon phenomenon characterized by dyspnea/arterial desaturation in the standing position, resolving in recumbency. Some patients present with Platypnoea-Orthodeoxia Syndrome in the early-or-late post-operative period after major lung resection (lobectomy/pneumonectomy). The main cause of Platypnoea-Orthodeoxia Syndrome is an intracardiac anomaly (Patent Foramen Ovalis/Atrial Septal Defect) leading to right-to-left shunt.

Bronchoscopical Repair of Tracheal Laceration Using Conventional Instrumentation: A Novel Technique.

Postintubation tracheobronchial laceration is a rare complication of endotracheal intubation. It requires early serial treatment in cases of pneumomediastinum with difficulty in ventilation to prevent mediastinitis and stricture. The surgical access to the posterior tracheal wall depends on the site of the laceration.

Platypnoea-orthodeoxia syndrome after pulmonary lobectomy: a rare entity with a difficult diagnosis.

Platypnoea-orthodeoxia syndrome (POS) is a rare clinical entity. It is characterized by position-dependent dyspnoea and oxygen desaturation in the upright position with orthodeoxia resolving in the supine position, and is mainly associated with cardiac defects. Only 9 cases of post-lobectomy POS have been reported in the literature.

Pericardial effusion in a young patient with newly diagnosed systemic lupus erythematosus and a mediastinal mass.

We present the case of a 32-year-old-woman who was admitted to the hospital for evaluation of pericardial effusion. The subsequent diagnostic workup revealed the presence of a mediastinal mass along with systemic lupus erythematosus (SLE). The patient underwent thymectomy, and histological evaluation of the resected mass revealed thymic follicular hyperplasia without evidence of malignancy.

Prognostic factors in thymic epithelial tumors undergoing complete resection.

Background: The prognostic factors in thymic epithelial tumors (TET) are investigated within a 27-year period in 104 patients submitted to surgical and pathologic complete resection of TET with a mean age of 53 +/- 14.6 years and a male to female ratio of 0.73.

Expression of the RNA-binding protein CRD-BP in brain and non-small cell lung tumors.

The coding region determinant-binding protein (CRD-BP) is an RNA binding protein that recognizes c-myc and IGF-II leader 3 mRNAs as well as the oncofetal H19 RNA. CRD-BP exhibits an oncofetal pattern of expression and has been detected in the majority of colon (81%), breast (58.5%) and sarcoma (73%) tumors.

Basaloid carcinoma, a rare primary lung neoplasm: report of a case and review of the literature.

Basaloid carcinoma of the lung is a rare primary neoplasm, first described in 1992. Basaloid carcinoma is an aggressive subtype of Non small cell lung cancer, with poor 5-year survival, even in stage I and II resected tumors. Differential diagnosis from small cell, Neuroendocrine large cell and poorly differentiated squamous cell carcinoma is difficult to be made.