Publications by authors named "Koskinen A"

Article Synopsis
  • Thyroid cancer (TC) has various histological types that impact patient survival differently, with improvements in relative survival rates noted in Sweden between 1999 and 2018.
  • Female patients generally have better survival rates compared to males and certain types, like follicular and oncocytic, show particularly high 5-year relative survival rates, though anaplastic cancer remains significantly more lethal.
  • Urgent diagnosis and treatment are critical for anaplastic TC due to its poor survival outcomes, highlighting the need for dedicated research and improved treatment pathways similar to those implemented in Denmark.
View Article and Find Full Text PDF

Objectives: We describe age-specific survival in thyroid cancer (TC) from Denmark, Finland, Norway, and Sweden over a 50-year period.

Design: Population-based survival study.

Methods: Relative 5-year survival data were obtained from the NORDCAN database for the years 1972-2021.

View Article and Find Full Text PDF

Objective: Patients undergoing heart surgery are at high risk of postoperative fluid accumulation due to long procedures and cardiopulmonary bypass. In the present study, we sought to investigate the prevalence of postoperative fluid accumulation and its relation to adverse events in patients undergoing cardiac surgery.

Methods: CAREBANK is prospective, single-center cohort study focusing on the adverse events after cardiac surgery.

View Article and Find Full Text PDF

Background: Cancers of the head and neck (HN) are heterogeneous tumors with incidence rates varying globally. In Northern Europe oral and oropharyngeal cancers are the most common individual types. Survival for HN varies by individual tumor type but for most of them survival trends are not well known over extended periods of time.

View Article and Find Full Text PDF

Background: Although nurse understaffing and limited nursing work experience may affect hospital patients' risk of mortality, relatively little longitudinal patient-level evidence on these associations is available. Hospital administrative data could provide important information about the level of staffing, nurses' work experience and patient mortality over time.

Objective: To examine whether daily exposure to nurse understaffing and limited nursing work experience is associated with patient mortality, using patient-level data with different exposure time windows and accounting for several patient-related characteristics.

View Article and Find Full Text PDF

Aims: Although seasonality has been documented for mental disorders, it is unknown whether similar patterns can be observed in employee sickness absence from work due to a wide range of mental disorders with different severity level, and to what extent the rate of change in light exposure plays a role. To address these limitations, we used daily based sickness absence records to examine seasonal patterns in employee sickness absence due to mental disorders.

Methods: We used nationwide diagnosis-specific psychiatric sickness absence claims data from 2006 to 2017 for adult individuals aged 16-67 ( = 636,543 sickness absence episodes) in Finland, a high-latitude country with a profound variation in daylength.

View Article and Find Full Text PDF

Objective: This study aimed to investigate the association between Parkinson's disease (PD) and occupational exposure to organic solvents generally and chlorinated hydrocarbons (CHC) in particular.

Methods: We assembled a Finland-wide case-control study for birth years 1930-1950 by identifying incident PD cases from the register of Reimbursement of Medical Costs and drawing two controls per case using incidence density sampling from the Population Information System, matched on sex, birth year, and residency in Finland in 1980-2014. Occupation and socioeconomic status (SES) were identified from national censuses.

View Article and Find Full Text PDF

Objective: This study aimed to compare the utility of risk estimation derived from questionnaires and administrative records in predicting long-term sickness absence among shift workers.

Methods: This prospective cohort study comprised 3197 shift-working hospital employees (mean age 44.5 years, 88.

View Article and Find Full Text PDF
Article Synopsis
  • The study analyzes thyroid cancer survival rates in Denmark, Finland, Norway, and Sweden over 50 years (1971-2020), looking at changes in incidence and mortality alongside survival data.
  • It found that while 1-year survival rates were initially lower than 5-year rates, they improved over time, with current survival rates reaching approximately 92.7% for men and 95.6% for women at 1 year, and 88.0% for men and 93.7% for women at 5 years.
  • The research indicates an overall increase in thyroid cancer survival, particularly in Denmark, and emphasizes the need for better early diagnosis and treatment of aggressive tumors to enhance 1-year survival rates.
View Article and Find Full Text PDF

Purpose: This register-based study examined the trajectories of depression or anxiety disorder-related work disability during and following long-term psychotherapy and identified sociodemographic factors that indicate membership in different trajectory groups.

Methods: Data were drawn from national registers (Statistics Finland, Social Insurance Institution of Finland). Participants included a random sample of Finnish working-age individuals (18-55 years) who started psychotherapy treatment between 2011 and 2014 and were followed for 5 years: 1 year before and 4 years after the onset of psychotherapy (N = 3 605 individuals; 18 025 person-observations across five time points).

View Article and Find Full Text PDF

Aims: This study aimed to compare the sickness absence (SA; over 10 days) rates of migrant and non-migrant care workers in Finland.

Methods: Two cohorts were randomly sampled from nationwide registers and analysed together in a three-year follow-up design (2011-2013, 2014-2016). The pooled data consisted of 78,476 care workers, of whom 5% had a migrant background.

View Article and Find Full Text PDF

Objective: To explore predictive factors of postoperative outcome of frontal sinus balloon dilation.

Study Design: Retrospective questionnaire study.

Setting: Department of Otorhinolaryngology-Head and Neck Surgery, Helsinki University Hospital and University of Helsinki, Finland.

View Article and Find Full Text PDF

Background: The excess risk of cardiovascular disease associated with a wide array of infectious diseases is unknown. We quantified the short- and long-term risk of major cardiovascular events in people with severe infection and estimated the population-attributable fraction.

Methods: We analyzed data from 331 683 UK Biobank participants without cardiovascular disease at baseline (2006-2010) and replicated our main findings in an independent population from 3 prospective cohort studies comprising 271 329 community-dwelling participants from Finland (baseline 1986-2005).

View Article and Find Full Text PDF

Background: Nurse understaffing may have several adverse consequences for patients in hospitals, such as health care-associated infections (HAIs), but there is little longitudinal evidence available on staffing levels and HAIs with consideration of incubation times to confirm this. Using daily longitudinal data, we analyzed temporal associations between nurse understaffing and limited work experience, and the risk of HAIs.

Methods: The study was based on administrative data of 40 units and 261,067 inpatient periods for a hospital district in Finland in 2013-2019.

View Article and Find Full Text PDF

Participatory shift scheduling for irregular working hours can influence shift schedules and sickness absence. We investigated the effects of using participatory shift scheduling and shift schedule evaluation tools on working hour characteristics and sickness absence. We utilized a panel data for 2015-2019 with 16,557 hospital employees (6143 in the intervention and 10,345 in the control group).

View Article and Find Full Text PDF

Objective: This study aimed to find out whether utilizing a shift schedule evaluation tool with ergonomics recommendations for working hours has favorable effects on the incidence of occupational injuries.

Methods: This 4-year prospective cohort study (2015-2018) consisted of a dynamic cohort of healthcare shift workers (N=29 237) from ten hospital districts and six cities in Finland. Working hour characteristics and occupational injuries were measured with daily registry data.

View Article and Find Full Text PDF

Background: The association between health and working hours is hypothesized to be reciprocal, but few longitudinal studies have examined changes in both health and working hour patterns over time. We examined combined trajectories of self-related health and two working hour patterns (working <35 h/week and working night shifts) and the extent to which these trajectories were predicted by employees' lifestyle and mental health.

Methods: Participants of this cohort study with a 8-year follow-up were 5,947 health care shift workers.

View Article and Find Full Text PDF

Background: Although needle biopsy is widely used in work-up of lymphadenopathy, lymph node excision (LNE) is often required especially in lymphoma diagnostics. LNE is an invasive procedure, which carries a potential risk of complications. However, comprehensive studies evaluating the spectrum and occurrence of complications are lacking.

View Article and Find Full Text PDF

Objectives: To examine the association of shift work with and without night work with breast cancer among women in the public sector.

Methods: Using the Finnish Public Sector cohort study (N=33 359, mean age of 40.6 years at baseline), we investigated the associations of shift work and potential confounders with incident breast cancer.

View Article and Find Full Text PDF

Background: National recommendations to decrease the health and safety risks of working hours are often given based on the increasing knowledge of the associations between working hour characteristics and health. However, the utilization of the recommendations, and their potential to change the actual working time patterns in healthcare sector is unclear.

Objective: We investigated the extent to which the national recommendations are utilized in shift scheduling, when they are integrated as a shift schedule evaluation tool into the shift scheduling software.

View Article and Find Full Text PDF

Background: Hospital physicians' work includes on-call duties to provide 24/7 health care. Previous studies using self-reported survey data have associated long working hours and on-call work with sleep difficulties. To reduce recall bias, we complemented survey data with payroll-based objective data to study whether hospital physicians' realized working hours are associated with sleep.

View Article and Find Full Text PDF

This study aimed to investigate trajectories of night shift work in irregular shift work across a 12-year follow-up among hospital employees with and without sickness absence (SA). The payroll-based register data of one hospital district in Finland included objective working hours and SA from 2008 to 2019. The number of night shifts per year was used in group-based trajectory modeling (GBTM).

View Article and Find Full Text PDF