[The phagocytic activity of the blood neutrophils in monkeys undergoing multiple irradiation].

The study of pathogenic activity of neutrophils under chronic low-dose irradiation (total doses were 0.84-24.99 Gy) was carried out.

[A cytogenetic study of the bone marrow cells from the 1st-generation offspring of irradiated monkeys].

Genetic structure was studied in cells of F1 posterity whose parents had survived irradiation exposure (2.2-6.6 Gy) 6-13 years ago.

[Long-term mutagenic effect in various types of somatic cells in monkeys exposed to low doses of penetrating radiation].

High level of chromosome aberrations has been determined in different types of somatic cells of monkeys which were subjected to general daily repeated low-capacity radiation (0.049-0.0078 Gy per a day) and accumulated summary doses of about 8.

[Cytogenetic study of the bone marrow and peripheral blood lymphocytes in monkeys in long-term gamma irradiation].

A comparative study of chromosome structures of bone marrow and peripheral blood cells has been carried out in 8 rhesus macaques (2-7 years of age), 4 of which survived after prolonged low-capacity (3.87 microA/kg) gamma irradiation, the total dose being 7.97 Gy (LD50/60).

[Dynamics of the chromosome aberrations in the bone marrow cells of monkeys after prolonged irradiation].

The effect of prolonged gamma-irradiation with doses of low intensity (3.87 microA/kg) was studied in the bone marrow cells of monkeys (Macaca rhesus). The cumulative dose was 214.

[Stable chromosome rearrangements in the somatic cells of monkeys subjected to acute radiation exposure].

Frequencies of stable chromosome rearrangements in bone marrow cells of rhesus monkeys (Macaca mulatta) have been determined for following time periods: from 0.25 to 6.0 and from 10.

[Incidence of chromosome aberrations in the bone marrow of monkeys and their progeny after exposure to aflatoxin B1].

A mutagenic effect of aflatoxin B1 (AFB1) was studied in somatic cells of primates. It is shown that AFB1 elevates the chromosome aberration frequency in bone marrow cells of two monkey species: Macaca mulatta and Papio hamadryas. Genome mutations were found in these experimental primates simultaneously with chromosome aberrations.

Frequency of chromosome aberrations in bone marrow of monkeys and their F1 after aflatoxin B1 injection.

A mutagenic effect of aflatoxin B1 (AFB1) in somatic cells of primates is investigated. It is shown that AFB1 elevated the frequency of chromosome aberrations in the bone marrow of two species of monkeys: Macaca mulatta and Papio hamadryas. Beside chromosome aberrations, genome mutations were found in these experimental primates.

[Spontaneous chromosome rearrangements in different kinds of rhesus monkey cells].

Spontaneous chromosome reconstructions were examined in bone marrow cells, peripheral blood lymphocytes and epithelial kidney cells from monkeys (Macaca mulatta). In normal monkeys, the chromosome reconstruction frequency was higher in epithelial kidney cells and lower in bone marrow cells. Peripheral blood lymphocytes occupied an intermediate position as regards the chromosome reconstruction frequency.

[Cytogenetic effect of protecting the bone marrow of mice and monkeys by using measured hypoxia in the action of low ionizing radiation doses].

The statistical reliable cytogenetic effect on bone marrow cells of mice and monkeys was achieved by means of dosage hypoxic hypoxia produced by breathing of gas hypoxic mixture containing 10% oxygen and 90% nitrogen (GHM-10). The effect was detested after total irradiation of mice and local irradiation of monkeys. The dose of irradiation was 100 rad (10 R/min and 17.

[Cytogenic consequences of irradiation in monkey kidney epithelial cells].

Cytogenetic consequence of irradiation was studied in epithelial monkey kidney cells in 3.5-9.0 years after repeated daily small dose irradiation (2.

[Structural changes in the marker chromosome of rhesus macaques subjected to irradiation].

Using 48 Macaca rhesus undergone acute single does and prolonged small dose daily irradiation, a long-term preservation of reconstructions in the pair of marker nucleolus-forming chromosomes has been shown. The animals were examined in different periods from irradiation, ranging from 3 months to 16.5 years.

[Structural changes in the chromosomes of the peripheral blood lymphocytes of monkeys subjected to daily long-term irradiation].

During the period that lasted from 4 to 11 years after the cessation of the long-term daily gamma-irradiation the frequency of chromosome rearrangements in peripheral blood lymphocytes of monkeys exceeded the control level. The number of rearrangements did not change significantly at different total irradiation dosses (from 826 to 3677 r). The main type of structural chromosome rearrangements were symmetrical chromosome exchanges.

[Chromosome aberrations in the cells of monkeys that have undergone acute irradiation with the use of chemical protection].

The rate and type of chromosomal aberrations in the bone marrow cells and circulating lymphocytes of the gamma-irradiated monkeys prophylactically treated with cystamine and mexamine 5-10 minutes before the irradiation was studied. The number of chromosomal aberrations 9-10 years after the gamma-irradiation (600-650 r) of the protected monkeys was similar to that in the animals irradiated without protection. Symmetrical chromosomal changes were most freuqent in all the monkeys long after the irradition, including the animals treated with radioprotectors.