Angiotensin receptor neprilysin inhibitor in chronic heart failure and comorbidity management: Indian consensus statement.

Heart failure (HF) is a significant public health concern characterized by notable rates of morbidity and mortality. Multimorbidity, ranging from 43% to 98% among HF patients, significantly impacts prognosis and treatment response. HF management requires a holistic approach, including guideline-directed medical therapy.

Minimally Invasive Approach to the Management of Recurrent Spontaneous Hemarthrosis After Total Knee Replacement: A Report of Two Cases.

Spontaneous recurrent hemarthrosis of the knee after total knee arthroplasty is an infrequent complication. Early recognition and prompt diagnosis are essential to avoid issues such as joint stiffness, chronic pain, and limited mobility. Conservative treatment methods are often effective.

Midterm functional outcomes of synthetic cartilage implant (SCI) arthroplasty for hallux rigidus.

Hallux rigidus is a common degenerative condition of first metatarso-phalangeal joint most commonly affecting patients above 50 years of age. The aim of our study is to evaluate the five-year results of synthetic cartilage implant (Cartiva) arthroplasty for hallux rigidus. A retrospective study of 70 patients who underwent synthetic cartilage implant interpositional arthroplasty were collected and analysed.

Stress Avulsion Fracture of the Patellar Tendon Following Open Reduction and Internal Fixation of a Transverse Patella Fracture With Cannulated Screws.

A stress-avulsion fracture of the inferior pole of the patella is rare. We report a case of a 65-year-old woman who underwent open reduction and internal fixation for a transverse fracture of the patella using cannulated screws inserted from the inferior pole of the patella. Subsequently, the patient developed an avulsion fracture of the inferior pole of the patella due to a stress riser from the prominent screw head.

Candida parapsilosis in Late Prosthetic Joint Infections Among Immunocompetent Patients: A Case Series.

Introduction: Fungal prosthetic joint infections (PJIs) are very rare in immunocompetent patients. PJI can present either early, delayed, or as late chronic infections. Diagnosis of fungal PJI presenting late is challenging due to the difficulty in isolation as well as the clinical presentation very similar to an aseptic loosening.

Stenosing Tenosynovitis Following Ankle Fracture Causing Progressive Acquired Tibialis Posterior Dysfunction: A Case Report.

Stenosing tenosynovitis of the ankle with osseous bone formation following an open reduction and internal fixation of the ankle is a rare clinical condition. We report a case of adult-acquired flat foot following an open reduction and internal fixation of a bi-malleolar fracture due to tibialis posterior tendon dysfunction caused by stenosing tenosynovitis. This was managed by open excision of the bony tunnel and debridement, along with calcaneal osteotomy and distalization of the tendon, resulting in good functional outcomes.

Lissencephaly and Advanced-Stage Congenital Cytomegalovirus Infection in a Neonate.

This case report investigates the management of a 24-week-old neonate with congenital cytomegalovirus (CMV) infection and its sequelae, including severe intrauterine growth restriction, thrombocytopenia, and brain anomalies, ultimately progressing to lissencephaly. The diagnostic challenges included delayed clinical suspicion of congenital CMV, which was not identified until after delivery through CMV DNA polymerase chain reaction, and differentiating its symptoms from other potential causes of the neonate's condition. Aggressive interventions included antibiotics, antiviral therapy with ganciclovir, and supportive measures such as intubation, CPR, respiratory support, blood transfusions, and management of coagulopathy.

Clinical Profile, Complications and Trends of Ocular Anaesthesia in a Multi-tier Ophthalmology Network in India: An Eight-Year Experience.

Introduction: To describe the clinical profile, complications and trends of ocular anaesthesia in a multi-tier ophthalmology network in India.

Methods: This retrospective hospital-based study included 417,622 patients presenting between January 2013 and December 2020. Patients who were administered either topical, local or general anaesthesia for ocular surgery in at least one eye were included as cases.

Septic Arthritis of the Sternoclavicular Joint.

Introduction: Sternoclavicular joint (SCJ) septic arthritis is a rare but rapidly fatal joint infection. Without proper medical or surgical management, it can progress to osteomyelitis, chest wall abscess, mediastinitis, or myositis.

Case Report: A 57-year-old male with a past history of intravenous drug use presented to the emergency department (ED) with chest tenderness of one week duration.

Potential implications of mobile applications in oral cancer.

The modern era has observed vast technological advancements with a definite impact on the health sector. There has been an upsurge in mobile applications (mApps) used for varied purposes. Many mApps are available that target different arenas in dentistry including a range of oral health issues, the most important being oral cancer.

The Role of Endoscopy in Investigating the Causes of Persistent Anaemia in Post-operative Fractured Neck of Femur Patients.

Introduction Post-operative anaemia in hip fracture patients has been associated with increased risk of blood transfusion, poorer functional outcomes, increased morbidity and mortality. Patients with persisting drop in haemoglobin after fractured neck of femur with no obvious source of blood loss are often referred for endoscopy to find the cause of anaemia. The reported incidence of perioperative acute upper gastrointestinal bleeding varies from 1 to 15%.

The outcomes of constrained total hip arthroplasty for recurrent dislocation of hip hemiarthroplasty.

Introduction: The incidence of hemiarthroplasty dislocation for fracture neck of femurs ranges between 1 and 15% and the one-year mortality is 49- 70%. Revision of hemiarthroplasty to total hip replacement using a constrained liner has shown to improve the morbidity and mortality rates. The aim of the study was to assess whether conversion of dislocated hemiarthroplasty to total hip replacement improve functional and one year mortality.

Not all roses are sweet-Pediatric ependymoma.

Ependymomas are rare malignant neoplasms that originate from radial glial cells within the central nervous system. Within pediatric central nervous tumors, ependymomas constitute the third most common entity with the majority occurring within the posterior fossa. Over the past decade, there have been monumental strides in classifying and grading central nervous tumors, specifically ependymomas.

Pulmonary Hypertension Registry of Kerala, India (PRO-KERALA): One-year outcomes.

Background: Short term outcomes of patients with pulmonary hypertension are not available from low and middle-income countries including India.

Methods: We conducted a prospective study of 2003 patients with pulmonary hypertension, from 50 centres (PROKERALA) in Kerala, who were followed up for one year. Pulmonary hypertension (PH) was mainly diagnosed on the basis of Doppler echocardiography.

as a rare cause of meningitis and ventriculoperitoneal shunt infection.

is an extremely rare pathogen responsible for ventriculoperitoneal shunt infection and meningitis. This young female patient with history of multiple shunt revisions in the past, came to us with shunt dysfunction and exposure of the ventriculoperitoneal shunt tube in the neck. The abdominal end of the shunt tube was seen migrating into the bowel during shunt revision.

Basal Ganglia Disease Mimicking Acute Encephalitis Syndrome Among Infants of Bodo Tribe, Assam.

We conducted a review of hospital records of infants with acute encephalitis syndrome with bilateral symmetrical basal ganglia infarcts, between 2011-2015, at a single center in Assam. Thiamine (as part of multivitamin injection) was used in the treatment of 23 infants and not used in 27; Only 1 (3.7%) infant died in the former group and 20 infants (86.

An analysis of mortality and survival of COVID 19 patients admitted to a tertiary care hospital in Maharashtra, India.

Background: After nine months of responding to the coronavirus disease-19 (COVID-19) pandemic, the scientific fraternity is yet to unravel the mystery of those who are at most risk from mortality. Despite resistance to wear masks, the global public health response has beaten the grimmer projections of millions of deaths. The present study seeks to analyze the survival of COVID-19 patients at a tertiary care hospital and identify the risk factors of mortality.

Single-Stage Revision With Fluconazole Monotherapy in Fungal Prosthetic Knee Joint Infections.

Fungal prosthetic joint infection is rare, and two-stage revision is usually advocated. We present our experience with 2 cases of fungal prosthetic knee joint infection presenting 25 months and 3 years after index surgery. Both patients were managed with single-stage revision arthroplasty and fluconazole monotherapy.

A Model of Care Optimized for Marginalized Remote Population Unravels Migration Pattern in India.

Background And Aims: Access to basic health needs remains a challenge for most of world's population. In this study, we developed a care model for preventive and disease-specific health care for an extremely remote and marginalized population in Arunachal Pradesh, the northeasternmost state of India.

Approach And Results: We performed patient screenings, performed interviews, and obtained blood samples in remote villages of Arunachal Pradesh through a tablet-based data collection application, which was later synced to a cloud database for storage.

Interventions to improve ergonomics in the operating theatre: A systematic review of ergonomics training and intra-operative microbreaks.

Musculoskeletal occupational injury is prevalent within the surgical community. This is a multi-factorial issue, but is contributed to by physical posture, environmental hazards and administrative deficiency. There is growing awareness of this issue, with several behavioural, educational and administrative techniques being employed.

Radiation dose reference card for interventional radiology procedures: Experience in a tertiary referral centre.

Background: Fluoroscopy-guided interventions can potentially increase radiation risk to patients, if awareness on angiographic imaging technique and radiation dose is neglected.

Aim: To develop patient radiation dose reference card from standardized imaging techniques for various radiology interventions performed using flat detector based angiography system.

Materials And Methods: Real-time monitoring of angiographic exposure parameters and radiation dose were performed for 16 types of radiological interventions.