[Predictors of external pancreatic fistulae after pancreatic resection].

Despite a significant decrease in postoperative mortality after pancreatic resections in recent years (5.2-15% after pancreatoduodenectomy and about 5% after distal pancreatectomy), incidence of postoperative complications remains high (30-50% and 22-50%, respectively). Postoperative pancreatic fistula is one of the most common and formidable complications.

[Short- and long-term outcomes of laparoscopic interventions in patients with colon cancer: single-centre experience].

Objective: To compare short- and long-term outcomes of treatment in patients with colon cancer undergoing laparoscopic and open surgery.

Material And Methods: There were 281 patients with colon cancer. All patients underwent open (n=144, 51.

[Outcomes of cardiac achalasia grade II-III management].

Aim: To analyze early and remote results of the new method of cardiac achalasia grade II-III management.

Material And Methods: Original surgical approach was applied in 21 patients with cardiac achalasia grade II-III.

Results: There were no any specific postoperative complications and deaths.

[Redoudenization with the formation of antireflux anastomosis in the surgery for operated stomach diseases].

This paper reports the results of surgical treatment of 39 patients with diseases of operated stomach including 26 (66.7%) men and 13 (33.3%) women aged 31-70 (mean 48.

[Functional status of the bile excretion system and upper gastrointestinal tract in patients with duodenal ulcer].

The research of functional condition of biliary tract in 35 patients suffered from gastroduodenal ulcers compared with 30 almost healthy patients was conducted. Disorders of motor function were found out in 13.2% patients in control group.

Association between TP53 gene ARG72PRO polymorphism and chromosome aberrations in human cancers.

It is well known that the TP53 gene considerably influences on DNA repair processes. Polymorphisms in the TP53 gene, particularly the well-known Arg72Pro in codon 72 of exon 4 (Ex4+119 G>C; rs1042522), can modify the functionality of the p53 protein and activation of DNA repair. Actually, polymorphic variants Arg and Pro were found to have different properties of regulation of TP53-dependent DNA repair target genes, that can effect various levels of chromosome aberrations in cancer patients with these genotypes.

[Proctectomy and sphincterolevatoroplasty in cancer of the inferioampular part of rectum with involvement of the anal canal].

Proctectomy with total mesorectumectomy, resection of the interior sphincter, deep parts of the external sphincter and bringing down were fulfilled according to an original authors' method in 7 patients aged from 38 to 78 years for cancer of the inferioampular part of the rectum with tumor located within the limits 8-35 mm from the anus (T3N1MO (n=1), T3NOM1 (n=1), T4N2M1 (n=1). Six months after operation conscious urge to defecation 1-2 times a day and containment of stools were noted and a year later it was possible to ignore urges during 15-30 min. In 5 patients T3NOM0--T3N1M0 relapse-free period for 3-5 years was noted.

[Transabdominal ultrasonic scanning in evaluation of liver parenchyma: new opportunities].

On suspicion of the diffusive liver lesions 117 patients have been performed a transabdominal ultrasound investigation with a visual estimate of the echogenicity of the structure of the liver's parenchyma in comparison with the echogenicity of the cortical substance of the kidney and with the determination of the homogeneity of the liver's structure on its different areas. For the purpose of the elevation of the self-descriptiveness and precision of diagnostics as well as for the reduction of the subjective estimation the authors carried out the evaluation of the structure of the liver's parenchyma and the cortical substance of the kidneys using the histography on the marked area. The elaboration of the efficient quantitative assessment of the changes of the liver's parenchyma allowed to relieve complications in differential diagnostics and to estimate the damage level of the organ's parenchyma objectively during the investigation.

[Low anterior resection of the rectum: a new method of forming the reservoir].

A method of forming the rectum reservoir after low anterior resection of the rectum has been developed, consisting in low anterior resection with mesorectumectomy, forming a reservoir from the colon, forming a rectosigmoid passage. The operation was made in 37 patients aged from 47 to 69 years for rectum cancer with the tumor localized in the middle and low ampular part. Complications in the early postoperative period appeared in 16.

[Study of gastroduodenal complex wealthy with help of transabdominal ultrasonography].

In the present work we report the results of gastroduodenal complex transabdominal sonography in grayscale mode with Doppler techniques in 237 patients. Sonographic criteria for normal and abnormal intensity of contents outflow from stomach to duodenum were defined, that can be applied in diagnostic algorithm for proximal gastrointestinal tract functional disorders.

[Current technology of surgical treatment of II-III stage esophageal achalasia].

Original method of surgical treatment of patients with II-III stage esophageal achalasia -- total demuscularisation of affected esophageal part, selective proximal vagotomy, and formation of invaginated valve from autologous tissues -- is analysed. Overall 39 patients aged 23 to 62 years with II (6) and III (33) stage esophageal achalasia have been operated. There were no specific postoperative complications.

New type of jejunal interposition method after gastrectomy.

Background: Total and subtotal gastrectomies are methods of choice in surgical treatment of gastric cancer. These ablative operations eliminate the gastric reservoir and severely alter digestive physiology.

Methods: We have created a unique method of reconstruction of "the jejunal pouch" following gastrectomy using the first loop of the jejunum together with the formation of antireflux anastomosis.

[Method of treatment of reflux-esophagitis after gastrectomy].

A new method of treatment of reflux-esophagitis developed for patients after gastrectomy has a distinctive moment: the formation of a restraining mechanism in the field of esophago-gastric anastomosis, without opening the intestinal tube lumen. The carried on trials of clinical application of the method have shown its high effectiveness for prophylactics ofjejuno-esophageal reflux both in the early and distant terms after operation. The method of operating was given a patent of the Russian Federation.

[Reconstructive jejuno-gastroplasty in the treatment of operated stomach disease].

The results of treatment of 205 patients with operated stomach disease were analyzed. Conservative therapy was effective in 71.7% patients.

[Surgical treatment of stage IV cardial achalasia].

An original method of surgical treatment of patients with stage IV cardial achalasia was developed. Seven patients aged 42 to 59 years underwent surgery according this method. Objective methods of examination and life quality study with GIQLI carried out 3 months to 5 years after surgery demonstrate satisfactory anatomic and functional results.

[Enteral tube feeding at the early postoperative period (stomach surgery)].

The article describes a comparative analysis of the efficacy of various variants of nutritive support in 115 patients with complicated gastroduodenal ulcers at the early postoperative period. 95 patients received enteral tube feeding, 50 of them receiving balanced isocaloric formulas and 45 of them receiving broths and decoctions as a nutritious substrate. The control group comprised 20 patients who received full parenteral feeding.

[Correction of the motor-evacuation function of the postoperative stomach in the early postoperative period].

We conducted the analysis of the results of surgical treatment of 255 patients with duodenal ulcers. In the early postoperative period the evacuation and motility function of the postoperative stomach was corrected with the use of the autonomous electrostimulator of the gastrointestinal tract (EAS GT) in all patients - in the main group (n = 125) and drug stimulation (cerucal 2.0 intramuscularly twice a day) and in the control group (n = 130).

[Choice of radical surgical method in patients with sutured perforated gastroduodenal ulcers].

Long-term results of suturing of perforated gastroduodenal ulcer in 364 patients were analyzed. Within 16 years after surgery recurrence of ulcer was seen in 215 (62.9%) patients.

[Restoration of nutritional status in patients with complicated course of ulcer during preoperative period].

The comparative analysis of the efficiency of the enteral tube feeding and parenteral feeding in 52 patients with the subcompensated stenosis of the pylorus was carried out. Satisfactory results were received in all groups of patients taking enteral and parenteral feeding. Consequently, the differences in the parameters of the catabolic index and general protein in the patients taking balanced food mixes rich in calories and 'usual feeding' were statistically significant.

[Surgical treatment of gastroesophageal reflux].

One hundred and seventy-five patients with gastroesophageal reflux disease (GERD) were treated, 144 (82.2%) of them underwent surgery. In 106 (73.

[Contribution to the methods of formation of pancreatojejunal anastomosis during pancreatoduodenal resection].

A method preventing a contact of the intestinal content and bile with the wound surface of the stump and pancreatic juice in the pancreatic ducts was proposed in order to prevent reflux of the infected intestinal content in the ducts of the pancreas. The work was fulfilled in experiment and in clinic. The article is well illustrated and recommended for publication as having a scientific and practical value.

[Surgical treatment of complicated duodenal ulcer: experience and prospects].

The article discloses the results of the surgery of 696 patients with completed duodenal ulcers. The organ-preserving treatment was provided for 31.8% of patients, and stomach resection was performed on 68.

[Method of selective proximal vagotomy].

A method of selective proximal vagotomy has been developed experimentally. It provides additional parasympathetic denervation of an acid-producing zone of the stomach by means of circular transsection of gastric and esophageal muscular membranes above and below cardial sphincter with forming of are flux esophageal-gastric valve. Clinical use of this method in 75 patients confirmed experimental data about a good function of the created valve and adequate decrease of acid production.

[Surgical treatment of gastric and duodenal ulcer disease with chronic duodenal obstruction].

One hundred and twenty-nine surgeries were performed from 1990 to 2001 for gastric (50) or duodenal (79) ulcers with chronic duodenal obstruction. Resection of 1/2 of the stomach by Bilrot-I was performed in 118 patients, pylorus-saving resection with creation of areflux valve in duodenal bulb--in 5, selective proximal vagotomy with duodenoplasty--in 6 patients. In early postoperative period complications were seen in 10 (10.