Publications by authors named "Kosei Shinoki"
Purpose: The association between maternal physique and prevalence of lactational mastitis (LM) in a large study population has not been reported. In this study, we aimed to evaluate the association between pre-pregnancy body mass index (BMI) and LM prevalence.
Methods: We analyzed data collected from participants enrolled in the Japan Environment and Children's Study, a nationwide birth cohort study conducted between 2011 and 2014.
Article Synopsis
- The study explores the link between sleep position and the occurrence of otitis media in infants, highlighting that sleep position may influence health outcomes.
- Data from the Japan Environment Children's Study involving 85,731 infants were analyzed, revealing a higher incidence of otitis media when infants slept in the prone position.
- The findings suggest that promoting safe sleep positions could help prevent otitis media among infants under 6 months old.
Article Synopsis
- The study investigated the link between atopic dermatitis in pregnant women and the risk of preterm births, focusing on those treated with ritodrine hydrochloride.
- Data from over 83,000 women with singleton pregnancies were analyzed, using self-reported questionnaires to define atopic dermatitis and multivariable logistic regression to assess preterm birth risks.
- Results showed that pregnant women with atopic dermatitis had lower odds of preterm birth before 37 weeks, indicating that atopic dermatitis might be associated with a decreased risk of preterm deliveries.
Objectives: Hypertensive disorders of pregnancy (HDP) are a significant cause of morbidity and mortality. This study aimed to investigate whether preconception dietary fiber intake is associated with new-onset HDP.
Study Design: We identified 84,873 (primipara, 33,712; multipara, 51,161) normotensive participants from the Japan Environmental Children's Study database who delivered between 2011 and 2014.
Article Synopsis
- The study investigates the link between breakfast habits during pregnancy and neurodevelopment in children, involving data from over 72,000 women in Japan.
- Results indicate that regular breakfast consumption is associated with better communication skills in children at age 3, particularly benefiting those in specific maternal daily energy intake groups.
- The findings suggest that maternal daily energy intake and the sex of the child can influence this association.
Background: There has been a recent decrease in the prevalence of infectious diseases in children worldwide due to the usage of vaccines. However, the association between cesarean delivery and infectious diseases remains unclear. Here, we aimed to clarify the association between cesarean delivery and the development of infectious diseases.
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- Maternal psychological distress, including depression and anxiety during pregnancy and postpartum, may impact children's cognitive development, but previous research has shown inconsistent results.
- * The study utilized data from the Japan Environment and Children’s Study to explore the relationship between maternal psychological distress (measured by the K6 scale) and cognitive development in 4-year-old children.
- * Findings indicated that persistent high distress levels (K6 scores ≥ 5) negatively affected language and social development in boys, while girls did not show significant differences in developmental quotients.
Article Synopsis
- - The study aimed to explore the link between high levels of urinary 8-hydroxy-2'-deoxyguanosine (U8-OHdG), a marker of oxidative stress, and the risk of preterm births (PTBs) in pregnant women.
- - Conducted as a prospective cohort study with data from over 92,000 women in Japan, the research categorized U8-OHdG levels into different groups and analyzed their association with PTB incidence.
- - Findings indicated that higher U8-OHdG levels were linked to an increased likelihood of PTBs, suggesting that oxidative stress may play a role in the occurrence of early births, particularly when excluding known causes of artificially induced PTBs.
Article Synopsis
- - The study analyzed the link between maternal intimate partner violence (IPV) before and during pregnancy and the development of autism spectrum disorder (ASD) in their 3-year-old children, using data from the Japan Environment and Children's Study.
- - It found that among nearly 80,000 offspring, 0.45% were diagnosed with ASD, with higher rates of physical IPV reported before conception compared to during pregnancy; specifically, physical IPV prior to conception was significantly associated with an increased risk of ASD.
- - The research highlights the importance of preventive care against physical IPV before pregnancy to support neurodevelopment in children, while indicating that psychological IPV does not show the same association with ASD development in the offspring.
Article Synopsis
- The study examined the link between nonreassuring fetal status (NRFS) during labor and long-term neurodevelopmental delays in children using data from nearly 73,000 women in Japan.
- Adjusted odds ratios indicated that NRFS was associated with personal-social issues in 3-year-olds, particularly for those born vaginally or via cesarean.
- However, this association did not hold for infants with better neonatal outcomes, suggesting that factors like delivery method and neonatal health may influence the relationship between NRFS and neurodevelopmental delays.
Article Synopsis
- The study aimed to analyze the differences in maternal characteristics and childhood outcomes between term and post-term births (after 37 weeks) regarding the use of tocolytic treatment.
- Data from 63,409 women in Japan was examined, revealing variations in maternal and obstetric outcomes between those who received tocolytic treatment and those who did not, but no significant differences in childhood developmental disorders.
- It was found that tocolytic treatment was linked to higher rates of offspring allergies, with an adjusted odds ratio of 1.08, indicating a slight increase in allergic conditions among children from treated mothers.
Article Synopsis
- A nationwide study in Japan analyzed data from 94,236 women with singleton births to evaluate the relationship between the timing of diagnosis for threatened preterm birth (TPTB) and the likelihood of preterm birth (PTB).
- The research categorized women by gestational age at TPTB diagnosis and parity, using logistic regression models to calculate the odds of PTB occurring before 37 and 34 weeks.
- Results indicated that the timing of TPTB diagnosis impacts PTB rates, with varying outcomes for nulliparous and multiparous women, highlighting the need for further research with comprehensive clinical data.
Article Synopsis
- - This study analyzed cord serum total cholesterol (TC) and triglyceride (TG) levels in Japanese newborns, using data from over 70,000 births collected between 2011 and 2014.
- - The findings showed that gestational age and birth weight significantly influenced cord blood TC and TG levels, with mean levels decreasing during the preterm period but increasing during the term.
- - Maternal factors such as age, health complications, and socioeconomic status were linked to variations in cord blood TC and TG levels, highlighting a lack of previous reference data for these lipid levels in Japan.
We evaluated the association between maternal prenatal folic acid supplement use/dietary folate intake and cognitive development in 4-year-old offspring (N = 3445) using data from the Japan Environment and Children's Study. Cognitive development was evaluated using the Kyoto Scale of Psychological Development 2001. Multiple regression analysis revealed that offspring of mothers who started using folic acid supplements pre-conception had a significantly higher language-social developmental quotient (DQ) (partial regression coefficient 1.
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- This study explored the relationship between maternal magnesium intake (MMI) and the occurrence of wheezing in 3-year-old children, hypothesizing that higher magnesium could reduce wheezing due to its anti-inflammatory properties.
- Data from 79,907 pregnant women in Japan were analyzed, categorizing MMI into various levels to assess its impact on wheezing incidence in children.
- The results indicated that higher MMI was slightly associated with an increased occurrence of childhood wheezing, suggesting that MMI might not significantly affect wheezing rates, and highlighting the need for further research on prenatal factors influencing childhood wheezing.
Background: Although maternal triglyceride (TG) is important for fetal growth, there are few large cohort studies investigating the relationships between maternal TG during pregnancy and neonatal outcomes.
Objectives: The objective of this study was to investigate the associations between maternal TG during the second and third trimesters and neonatal outcomes including preterm birth (PTB), low birth weight (LBW), small for gestational age (SGA) and large for gestational age (LGA).
Methods: This was a prospective birth cohort study using data of the Japan Environment and Children's Study included data of births from 2011-2014 in Japan including 79,519 pairs.
Objective: To evaluate the association between maternal asthma (MA) and obstetric complications, while considering subdivided total serum immunoglobulin E (IgE) levels.
Methods: Data of the participants enrolled in the Japan Environment and Children's Study between 2011 and 2014 were analyzed. In total, 77,131 women with singleton live births at and after 22 weeks of gestation were included.
The hygiene hypothesis suggests that pet exposure is effective in preventing allergic disease, and some studies have reported the beneficial effects of dog exposure during fetal development or early infancy on food allergy. However, the effects of exposure to pets other than dogs on the kinds of food allergies remains unaddressed. This study aimed to explore the effect of exposure to various species of pets on the risk of food allergies.
View Article and Find Full Text PDFIntroduction: This study aimed to assess congenital anomalies among infants from 2011 to 2014 in Fukushima and compare the assessment with that from other geographical regions in Japan.
Methods: We used the dataset of the Japan Environment and Children's Study (JECS), which is a nationwide prospective birth cohort study. For the JECS, participants were recruited through 15 regional centers (RC), including Fukushima.
Maternal prenatal psychological distress, including depression and anxiety, may affect offspring's motor/cognitive development. However, research findings have been inconsistent. We used a dataset from the Japan Environment and Children's Study to evaluate associations between maternal six-item Kessler Psychological Distress Scale (K6) scores and motor/cognitive development among offspring at two years of age.
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- * In a study involving 412 mothers, the researchers measured neutralizing antibody titers (NATs) and epitope-specific antibody (ESA) levels in maternal and cord blood, finding that levels in cord blood were slightly higher.
- * The findings suggested a strong correlation between maternal and cord blood NATs and ESA levels, particularly for a specific site on the RSV F protein, indicating that mothers effectively transfer protective antibodies to their infants.
This study evaluated the association between labour duration (LD) and incidence of low neonatal Apgar scores and foetal acidosis. Data of 37,682 women with full-term singleton spontaneous vaginal deliveries from the Japan Environment and Children's Study were analysed. Women were classified according to the median LD as nulliparous (< 10 or ≥ 10 h) or multiparous (< 5 or ≥ 5 h) and further into five subcategories: nulliparous (< 10.
View Article and Find Full Text PDFAim: Hypertensive disorders of pregnancy (HDP) are a crucial cause of morbidity and mortality. We aimed to examine whether preconception carbohydrate intake is associated with new-onset HDP and small for gestational age (SGA) births.
Methods: We identified 93 265 normotensive (primiparous, 37 387; multiparous, 55 878) participants from the Japan Environmental Children's Study database who delivered between 2011 and 2014.