Comparison of the bactericidal effects of quinolones against low-susceptible .

The increasing incidence of with decreased susceptibility to quinolones (quinolone low-susceptible ) in Japan has raised concerns about therapeutic failure. Thus, assessment of effective antimicrobial agents is necessary to establish an effective therapeutic strategy against resulting infections. In this study, bactericidal effects of quinolones on low-susceptible strains were evaluated using time-kill curve analysis.