[Lymphocyte reaction and humoral immune response to brain specific protein in children with pathology of the central nervous system].

Blood lymphocyte reaction to brain specific protein (BSP) in vitro and anti-brain antibodies (AB) levels were studied in newborns and infants with perinatal central nervous system (CNS) damages of various severity. A relationship between severity of CNS damages and a lymphocyte reaction to BSP as well as immuno-regulative index (IRI) changes. A combination of high AB to BSP levels with IRI elevation after cells incubation with BSP was found to be a favorable prognostic sign.