Polarisation changes in guided infrared thermography using silver halide poly-crystalline mid-infrared fibre bundle.

Broadband mid-infrared (B-MIR) thermography using fibre optic waveguides can be critical in real-time imaging in harsh environments such as additive manufacturing, personalised medical diagnosis and therapy. We investigate the polarisation effect on thermal measurements through poly-crystalline fibre bundle employing a simple broadband cross-polarisation configuration experimental set-up. Silver halide poly-crystalline fibres AgClBr (0 ≤ ≤1) (AgClBr-PolyC) have very wide transmission bandwidth spanning over the spectral range from 1 µm up to 31 µm FWHM.

Loss of MECP2 Leads to Activation of P53 and Neuronal Senescence.

To determine the role for mutations of MECP2 in Rett syndrome, we generated isogenic lines of human induced pluripotent stem cells, neural progenitor cells, and neurons from patient fibroblasts with and without MECP2 expression in an attempt to recapitulate disease phenotypes in vitro. Molecular profiling uncovered neuronal-specific gene expression changes, including induction of a senescence-associated secretory phenotype (SASP) program. Patient-derived neurons made without MECP2 showed signs of stress, including induction of P53, and senescence.

Draft genome sequences of strains SMB35, sp. MH3R3-1 and sp. SMB17 from the Verkhnekamsk potash mining region of Russia.

Halomonads are moderately halophilic bacteria that are studied as models of prokaryotic osmoadaptation and sources of enzymes and chemicals for biotechnological applications. Despite the progress in understanding the diversity of these organisms, our ability to explain ecological, metabolic, and biochemical traits of halomonads at the genomic sequence level remains limited. This study addresses this gap by presenting draft genomes of SMB35, sp.

[New antioxidants as neuroprotective agents for the treatment of ischemic brain injury and neurodegenerative diseases].

Central nervous system disorders are the leading cause of mortality and disability in the world. Unfortunately, the possibility of pathogenetic therapy is limited and it is important to search for new drugs with neuroprotective mechanism of action. One of the most promising groups of drugs are antioxidants--substances that can neutralize free radicals and reduce oxidative stress.

[Molecular biological characterization of biphenyl-degrading bacteria and identification of the biphenyl 2,3-dioxygenase α-subunit genes].

Bacterial isolates from soils contaminated with (chlorinated) aromatic compounds, which degraded biphenyl/chlorinated biphenyls (CB) and belonged to the genera Rhodococcus and Pseudomonas were studied. Analysis of the 16S rRNA gene sequences was used to determine the phylogenetic position of the isolates. The Rhodococcus cells were found to contain plasmids of high molecular mass (220-680 kbp).

[Destruction of aromatic hydrocarbons by the Rhodococcus wratislaviensis KT112-7 strain isolated from waste products of a salt-mining factory].

The destruction of aromatic hydrocarbons by the Rhodococcus wratislaviensis KT112-7 strain isolated from technogenic mineral waste products of the BKRU1 Uralkalii factory has been investigated (city of Berezniki, Perm krai). The R. wratislaviensis KT112-7 was shown to utilize increased concentrations of ophthalic (o-PA) (8 g/L) and benzoic (BA) (3.

[Diagnosis of different stages of epileptogenesis by fractal EEG analysis].

The diagnostic evaluation of brain activity disturbances using fractal EEG analysis was performed in 95 patients with different stages of epileptogenesis. The control group included 30 normals. Authors have shown the possibility to determine phases of the development of epileptic process according to the peculiarities of the dynamics of main EEG band power fluctuations with the spectrum in the form of 1/f(β).

Multifractal analysis as an aid in the diagnostics of mental disorders.

The digitalization of EEGs (electroencephalogram) has showed new possibilities for analyzing electrical activity of brain. This has offered new methods, e.g.

[Neuroimmunopathological mechanisms of preclinical epileptogenesis and their correction by cycloferon].

The peculiarities of immunologic processes and immunocorrecting potential of Cyclopheron were studied in 62 patients with preclinical epileptogenesis. Using clinical, EEG and biochemical examination, expression of epileptogenesis was estimated as regressed, compensated, increasing, decompensated. Preclinical stage of epilepsy was accompanied by disturbance of immunological brain reactivity the expression of which was correlated with a level of compensative epileptogenesis manifestation.

[Fractal diagnostics of disturbances in the alpha-rhythm dynamics in patients with epilepsy].

A new method for analyzing the chaotic component of EEG is proposed. The method is based on estimating the fractal dimension of fluctuations of alpha-rhythm power (the square of amplitude). It is shown that the dimensions of the background EEG fragments for epilepsy patients is significantly higher than that in norm, indicating a disbalance of cerebral mechanisms that control the alpha-activity in this disease.

[Changes in EEG induced by prolonged hyperventilation in humans].

The data obtained revealed a significant augmentation of the EEG slow-wave activity following a 32-minute hyperventilation in neurologically healthy subjects. In 43% of the subjects, on the 8th minute of the hyperventilation a generalised paroxysm of the delta-activity occurred.