Publications by authors named "Koroush Soleimannejad"
Background: Reduction of permanent or transient cerebral blood flow may lead to some structural and functional changes of the brain, causing high mortality and morbidity. The aim of this experimental study was to investigate the effects of hydroalcoholic extract of Nigella sativa (NS) on markers of cerebral angiogenesis in rats induced by global brain ischemia.
Methods: Thirty-two male Wistar rats (250 ± 20 g) were randomly divided into 4 groups: group 1, control group receiving only normal saline; group 2, sham group undergoing surgery and stroke induction without treatment; and groups 3 and 4 treated with 10 and 20 mg/kg NS, respectively, after induction of stroke.
Background: Previous studies have reported endothelial dysfunction and inflammatory cytokine in heart failure patients (HF).
Objectives: The purpose of this study was to determine the effects of creatine monohydrate and exercise on inflammatory and endothelial dysfunction markers among HF patients.
Patients And Methods: One hundred patients were prospectively randomized into two groups: Intervention group which received 5 grams/day creatine monohydrate and exercised for 8 weeks; and control group which did not receive any interventions.
The effects of perfluorocarbon (PFC) on paraquat (PQ) induced acute lung injury (ALI) was evaluated among rats. Twenty four Wistar rats were divided into 4 groups: control group injected by saline physiologic 0.9%, PFC group injected by Perfluorocarbon, PQ group injected by PQ and PQ+PFC group injected by PFC one hour after receiving paraquat.
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- Previous studies have shown that phthalic acid (PA) is harmful to heart health, but the impact of prenatal exposure to PA on heart structure and function had not been explored before.
- In this study, pregnant rats were divided into groups to assess the effects of different levels of PA exposure on their offspring's heart markers, oxidative stress, and coronary artery structure.
- Results indicated that increased PA exposure led to significant weight reductions in both body and heart, elevated heart rates and blood pressure, thicker arterial walls, and higher oxidative stress levels, suggesting detrimental effects on vascular function and nitric oxide activity in the offspring.