Correlation between asthma severity and serum IgE in asthmatic children sensitized to Dermatophagoides pteronyssinus.

Background: We undertook this study to test the possible correlation between serum concentration of total and specific IgE antibodies and asthma severity in asthmatic children sensitized to the house dust mite Dermatophagoides pteronyssinus.

Methods: The study included 157 asthmatic children aged 5-15 years (8 +/- 3 years). Clinical diagnosis was based on personal and family history, physical examination, pulmonary function testing and skin tests.

Thrombopoietin and interleukin-6 in children with pneumonia-associated thrombocytosis.

Background: The aim of this study was to investigate why some, but not all, children develop thrombocytosis during the course of pneumonia.

Methods: The retrospective study included 40 healthy children and 75 children with pneumonia: 17 patients with platelet count within the reference values, i.e.

[Bronchial impairment of main bronchus by aspiration of ferrous sulphate tablet].

The late occurrence of broncial impairment in two children who had aspirated ferrous sulphate tablet ih presented. Local release of cytotoxic oxidant radicals led up to tissue necrosis and consequently to bronchial stenosis and obliteration. Bronchoscopy in the first child confirmed total obliteration of the left main bronchus eleven months after aspiration of iron tablet, and pulmectomy had to be done.