[Klebsiella pneumoniae adhesion to epithelioid cells in vitro].

The adhesion of K. pneumoniae K24 capsular strain No. 6723 onto subcultured epithelioid human kidney cells RN was studied overtime by light microscopy and by transmission and scanning electron microscopy.

[Influence of hemolytic plasmids on the development of the "killing" effect in various species of enterobacteria].

Experiments on isogenic strains of different enterobacterial species, both carrying hemolytic plasmids and free from them, have demonstrated that their "killing" effect on mice is linked with the yield of hemolysin and does not depend on the origin of Hly plasmids or the chemotype of bacteria. Plasmid p IE 567 coding the synthesis of alpha-hemolysin has been shown to be capable of expression in Enterobacter aerogenes, Hafnia alvei and Salmonella typhimurium strains, but E. aerogenes 3/43, H.

[Electron microscopic study of the interaction of nephritogenic strains of Escherichia coli carrying D-mannose-resistant fimbriae with the cells of a human kidney line].

The electron-microscopic study revealed that nephritogenic E. coli having L-mannose-resistant fimbriae contacted with subcultured human renal cells due to the interaction of fimbriae with microvilli and, less frequently, with the cytoplasmic membrane surrounding the main part of the cell, as well as with the electron-opaque fibrillar material in the intercellular space. The possibility of very close interaction was demonstrated; in some cases this interaction was so close that the outlines of bacterial and epitheloid cells followed each other, the invagination of the external membrane of the host cell being sometimes observed.

[Characteristics of Proteus, Klebsiella, Enterobacter and Citrobacter strains isolated in urological infections].

The comparative study of more than 300 Proteus, Klebsiella, Enterobacter and Citrobacter strains isolated from patients with urological infections and parenteral infections of other localization, as well as from the feces of healthy persons has been carried out. The strains causing inflammatory processes in the urinary tract have been shown to possess no strict specificity. The ability of opportunistic enterobacteria to cause urinary tract lesions is their polydeterminant property ensured by the combination of different factors.

[Antibiotic resistance of uropathogenic strains of E. coli isolated from patients in the USSR and the People's Republic of Bulgaria].

The MIC of benzylpenicillin, ampicillin, ceporin, streptomycin, kanamycin, gentamicin, tetracycline, rondomycin, rifampicin, chloramphenicol, nalidixic acid, orafuran, furacin and furazolidon with respect to E. coli strains isolated from urological patients were determined and compared with those isolated from patients with other localization of inflammatory processes and the feces of healthy persons. It was shown that the strains isolated from the urine of the urological patients were characterized by higher levels of the drug resistance and as a rule were polyresistant.

[Significance of the ability of E. coli to alter capillary permeability for the reproduction of pyelonephritis in mice].

Experiments in a number of biological models showed that the cultures of E. coli isolated from the urine of children with pyelonephritis had a varied spectrum of pathogenic properties. Histologically confirmed pyelonephritis induced by intravenous infection in CBA mice, treated with 5% glucose by the method of Montgomerie et al.