Fetal sigmoid colon mesentery - In relevance in fetal ultrasound application. A pilot study.

Introduction: Ultrasound examinations during pregnancy are routine procedures used to detect fetal congenital malformations. Ultrasound monitoring of sigmoid colon mesenterial development could be useful for early detection of subjects at risk of sigmoid colon volvulus.

Objective: The aim of our paper was to assess the sigmoid colon length, and sigmoid colon mesentery width and height in the late fetal period, and, using the results, to estimate the surface area of the mesocolon (in mm) in living fetuses.

Typology of the antegonial notch in the human mandible.

Background: Surgical treatment for serious malocclusions and fractures of the organ of mastication is a golden standard in medicine. Procedures performed on the mandible require detailed knowledge of the anatomy of the organ. Antegonial notching constitutes a serious technical challenge for surgeons.

Data dimensionality reduction in anthropometrical investigations.

Background: Very often it is necessary to make a decision or to establish a diagnosis on the basis of great amounts of different kinds of data. In this paper the principal component analysis procedure was applied to anthropometrical data analysis.

Objectives: The aim was to simplify the process of decision making by data dimensionality reduction.

[Interleukin-17 concentration in serum and urine of children with idiopathic nephrotic syndrome].

Unlabelled: T-cells and their cytokines play an important role in the pathogenesis of idiopathic nephrotic syndrome (INS) in children. IL-17 secreted by activated CD4+ Tcells induces production of proinflammatory mediators, enhances T-cell-mediated immune responses and Th1 type reactions. The aim of the study was to evaluate IL-17 concentrations in serum and urine of children with INS and determine the possible role of this cytokine in the course of disease.

A controlled, double-blind, randomized study on the efficacy of Lactobacillus plantarum 299V in patients with irritable bowel syndrome.

Background: Irritable bowel syndrome (IBS) is a widespread functional disorder of the digestive tract. Its aetiology is unknown and therapeutic options are limited. Recent reports suggest that probiotics may have a role in regulating the motility of the digestive tract.

Impact of functional dyspepsia on quality of life and health care consumption after cessation of antisecretory treatment. A multicentre 3-month follow-up study.

Background: The impact of response to treatment on subsequent symptoms, quality of life, health care consumption, and absence from work in functional dyspepsia is unknown.

Methods: Patients with functional dyspepsia from Denmark, France, Germany, The Netherlands, Hungary, and Poland (n = 567 (215 men), 18-80 years old) were followed up for 3 months after a 4-week treatment trial with omeprazole (20 mg or 10 mg) or placebo. The patients were blinded to the initial treatment.

Efficacy of omeprazole in functional dyspepsia: double-blind, randomized, placebo-controlled trials (the Bond and Opera studies).

Background: The efficacy of H2-receptor antagonists in functional dyspepsia is equivocal and the therapeutic place of proton pump inhibitors in functional dyspepsia is unknown.

Aim: To evaluate the efficacy of proton pump inhibitor therapy in functional dyspepsia.

Methods: Patients (n = 1262) with a clinical diagnosis of functional dyspepsia (persistent or recurrent epigastric pain or discomfort for at least 1 month and a normal upper gastrointestinal endoscopy) were randomized to receive omeprazole 20 mg, 10 mg or identical placebo, for 4 weeks.

Is Helicobacter pylori infection a risk or protective factor for mucosal lesions development in patients chronically treated with acetylsalicylic acid?

The interaction between ASA and H.p. as the strongest irritants to gastric mucosa has not been sufficiently documented to date.

[Alcoholic hepatitis].

The character is presented of the changes in the pathomorphological picture of alcoholic hepatocellular damage. The most frequently observed forms of clinical picture of alcoholic hepatitis are discussed. In the diagnosis of this nosological entity the role is stressed of liver biopsy as the method making possible obtaining of the most reliable diagnostic-prognostic information.

[Myeloblastoma of the brain and spinal cord in a patient with acute myelomonocytic leukemia].

A case of the myeloblastoma involving brain and spinal cord in a patient with acute myelomonocytic leukemia is reported. Numerous mitoses within the tumor provide an evidence for local cell proliferation in the neoplasm. Surgery combined with radiotherapy is suggested as the most efficient modality of the treatment.

Application of a multistage classifier to the diagnosis of some occupational disease groups.

This paper describes the basic concept of a multistage classifier and gives the results of the application of this approach to the diagnosis of vibratory syndrome and other diseases with similar symptoms. The multistage classifier was applied to classification of the most informative symptoms at particular stages of classification.

[The mechanism of cell proliferation in acute (immature-cell) leukemia].

In 40 patients with acute leukaemias the 3H-thymidine and mitosis indices were determined in the population of blast cells in bone marrow and the cellularity of bone marrow was determined. The studies were carried out in the first episode of the disease before treatment and in some patients (13) they were repeated during relapse after remission or improvement. The results showed that proliferative activity of blast cells was reduced in relation to precursors of normal granulopoiesis in all forms of acute leukaemia.

The parameters of cellular proliferation in acute (immature-cell) leukemias.

In 20 patients with acute leukemia the 3H-thymidine labelling index and the mitotic index were determined in the population of leukemic blast cells and the degree of bone marrow infiltration was evaluated. Determinations were carried out in acute stage of the disease and in 4 cases additionally during improvement or remission and then during subsequent exacerbations. In the acute phase of the disease both indices were low in comparison with the indices obtained in normal granulocytopoiesis.