[Glutathione-dependent enzymes and glucose-6-phosphate dehydrogenase of blood in patients with lymphosarcoma (non-Hodgkin's disease)].

Activities of glutathione-dependent enzymes and glucose-6-phosphate dehydrogenase (GPDH) were studied in blood of the patients with lymphosarcoma (LS). The activity of glutathione reductase (GR), glutathione dehydroascorbate reductase (GDAR), gamma-glutamyltranspeptidase (GGT) and G6PDH in plasma, leucocytes, lymphocytes and erythrocytes of peripheral blood in 30 patients (42-56 years) with LS and in 20 healthy have been determined with spectrophotometric methods (Humalyzer 2000 DE). Leucocytes and lymphocytes were separated from blood using Boyum method.

[MALT-lymphomas with primary gastric focus].

The peculiar features of the clinical course and treatment of primary gastric MALT-lymphoma in 7 patients are discussed. Diagnosis was established by morphological examination of resected material. Six patients had low-grade tumor while one showed signs of blast-transformation.

[Non-Hodgkin's lymphomas of the spleen and their pathomorphosis following splenectomy].

Clinico-morphological correlations in non-Hodgkin's splenic lymphomas (NHL) have shown that a clinical course and hematological symptoms of splenic NHL correlate with a morphological variant of disease. Blast forms have a more aggressive course. Data on the clinical pathomorphosis of splenic NHL after splenectomy suggest the necessity of administration of postoperative chemo- and radiotherapy for induction of complete remission and improvement of long term therapeutic results.

[Therapy against relapse in generalized lymphoblastic and immunoblastic lymphosarcomas in complete remission].

The authors present the results of the COP therapy of 85 patients with generalized lymphoblastic and immunoblastic lymphosarcomas. Antirelapse therapy with cyclophosphamide and reinduction courses according to the COP scheme and COP reinduction courses only increase the period of remission. A necessity of antirelapse therapy after achieving a complete remission is substantiated.

[Malignant histiocytosis. Report of a case].

A case of malignant histiocytosis in a man of 32 is described. The diseases had a rapid course, showed marked signs of intoxication, generalized lymphadenopathy, hepatomegaly, jaundice, leukopenia, thrombocytopenia. Specific infiltration with atypic histiocytes with phagocytosis of erythrocytes and their debris, leukocytes, and lipids was found in the lymph nodes, skin, bone marrow, liver, kidneys, heart muscle, and along the lung blood vessels.

[Effect of pregnancy on the course of lymphogranulomatosis].

The relationship of pregnancy and the course of Hodgkin's disease is discussed on the basis of 30 cases. 16 femalles became pregnant during complete remission: in 10 out of them, remission followed radical radiation therapy. Hodgkin's disease was diagnosed during pregnancy in 11 cases and within the first several weeks after delivery in 3 cases.

[Morbidity of nonlymphogranulomatous lymphomas in the Moldavian SSR].

Under study is the incidence of nonlymphogranulomatous lymphomas in the Moldavian SSR for a 10-year period depending on sex, age and nationality. Nonlymphogranulomatous lymphomas are more frequently observed among the urban population, and more often in males, the age peak among persons of both sex being over 60. There is a tendency to the increased incidence of this affection.

[Clinical aspects and morphology of sinus histiocytosis of the lymph nodes].

Based on the analysis of the literature data and personal authors' observations, the clinico-morphological signs of sinus histiocytosis are described. Also, the kinetics of the disease and a histological picture of the involved lymph nodes are shown at different stages of the process development. The necessity of lymph nodes biopsy in all cases suspicious of malignant lymphoma is emphasized.

[Morbidity and prevalence of lymphogranulomatosis in the Moldavian SSR].

The results of studies on the morbidity and incidnece of lymphogranulomatosis in Moldavian SSR during 10-year period depending on sex, age and type of the population are described. It is emphasized that lymphogranulomatosis is a comparatively rare lesion, more frequently it is encountered among urban population, in males in particular, with an age peak among persons of both sex older than 60 years. No tendency to any rise in the morbidity indices was noted.