Publications by authors named "Korchi F"
Objective: Our case-control study aimed to access the potential association of insertion/deletion (I/D) ACE (angiotensin converting enzyme) gene polymorphism with myocardial infarction (MI) risk of occurrence among a sample of Moroccan patients, especially young ones.
Results: Distribution of I/D ACE gene variant among cases vs controls, showed that healthy controls carried out higher frequency of wild type allele I compared to cases (23.5% vs 21.
Coagulation factor Leiden mutation has been described as a common genetic risk factor for venous thrombosis; however, this mutation was reported to be practically absent in an African population. Recently, a novel non-sense mutation in the gene encoding factor V has been associated with the risk of occurrence of cardio-cerebrovascular diseases such as stroke and venous thrombosis. The aim of the present study was to investigate whether the factor V Leiden (FVL) and C2491T non-sense mutations are associated with the risk of developing myocardial infarction.
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- Myocardial infarction (MI) is a major cause of death globally, linked to both genetic and environmental factors.
- This study examined the connections between specific genetic polymorphisms (C677T and prothrombin) and the risk of developing MI in 100 patients versus 182 healthy individuals.
- Results indicated a significant association of the prothrombin polymorphism with increased MI risk, suggesting it could serve as a genetic marker, while no link was found for the C677T polymorphism, highlighting the multifactorial nature of MI.
Background: Myocardial infarction (MI) is a common multifactorial disease. Numerous studies have found that genetic plays an essential role in MI occurrence. The main objective of our case-control study is to explore the association of G894T eNOS (rs1799983), 4G/5G PAI (rs1799889) and T1131C APOA5 (rs662799) polymorphisms with MI susceptibility in the Moroccan population.
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- * The study involved 101 patients with hypertension and 102 healthy controls, utilizing genetic analysis methods to assess the MTHFR C677T genotypes, finding a significant association between the mutant 677TT genotype and increased hypertension risk.
- * The results indicated that having the homozygous 677TT variant was linked to a higher likelihood of developing hypertension, particularly in those with a family history of heart disease, suggesting the need for larger studies to validate these findings.
The application of hypochlorite for the removal of soluble COD, phenolic and polyphenolic like compounds, and other organic compounds responsible for the olive mill wastewater (OOWW) colour has been experimentally studied. After the OOWW filtration on a sand column, the effluent was subjected to a fast liming under optimal conditions. Lime application reduced polyphenols, COD and SS contents to half of their initial values but an important blackening of the treated OOWW was observed, especially when adding high concentrations of lime (10% (W/V) and 15% (W/V)).
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