Gaucher's disease is the most common lysosomal storage disorder due to a deficiency of glukocerebrosidase activity. It leads to an accumulation of glukosylceramide within the cells of the the reticuloendothelial system. Gaucher's disease is divided into three subtypes based on clinical symptoms.
View Article and Find Full Text PDFPurpose: The aim of the study is to evaluate the dynamics of axial elongation of pseudophakic eyes and changes in refraction pseudophakic eyes in children after monocular or binocular cataract surgery.
Material And Methods: the observations of 79 children (158 eyes) aged from 4 to 18 years (mean 9.7 +/- 0.
The Aim: the history and clinical findings of 3.5 and 5.5-years old siblings with gyrate atrophy (GA) of the choroid and retina are presented.
View Article and Find Full Text PDFThe aim of the study was to compare the results of tear film volume, conjunctival and corneal state of children eyes both treated with beta-blocker and healthy ones. We have examined 40 eyes of 20 children at the age from 7 to 17 years. Group I - 20 glaucomatous eyes treated with 0.
View Article and Find Full Text PDFPurpose: To examine the influence of intraocular pressure (IOP) decreasing after trabeculectomy on the retinal nerve fiber layer thickness (RNFL) in glaucoma in the youth.
Material And Methods: Nineteen eyes of 12 patients at the age from 10 to 18, mean 13.6 years, treated for juvenile glaucoma were examined.
Several mutations of CYP1B1 gene, a member of cytochrome P450 gene family, have been associated with occurrence of primary congenital glaucoma. The aim of presented work was to investigate CYP1B1 gene exon III mutations in 72 unrelated Polish patients with primary congenital glaucoma (C), juvenile glaucoma (J) and juvenile glaucoma suspects (P). In one patient we have detected homozygous duplication of 10bp at nucleotide 8046 resulting in synthesis of truncated protein, first found among the polish population.
View Article and Find Full Text PDFPurpose: To estimate the central corneal thickness in young patients and to evaluate the relationship between the intraocular pressure (IOP) and pachometry.
Patients And Methods: Eighty eyes of 40 children at the age from 9-18 years, mean 13.75 were examined.
Purpose: Comparison of the effectiveness and safety of cyclocryocoagulation and transscleral contact cyclophotocoagulation with diode laser (TSCPC) in children.
Patients And Method: Sixty nine eyes of 60 children at the age from 4 months to 16 years were examined. Majority of patients was aphakic after congenital, traumatic and complicated cataract extraction.
Purpose: To compare anatomical and functional state of eyeballs after congenital cataract extraction and heparin-surface-modified PMMA (HSM-PMMA) or PMMA implanted lenses and to conclude, which type of implants is more advantageous in young patients.
Materials And Methods: 42 eyes of 30 children at the age of 3-16 years with congenital or developmental cataract after extraction and IOL implantation: I group--HSM-PMMA lenses in 24 eyes, and PMMA lenses in 18 eyes--II group. Mean age in the I group was 6 years and in the II group 8 years, p = 0.
Purpose: Evaluation of the influence of intraocular pressure (IOP) after trabeculectomy on the axial length and refraction of eyeballs in children with primary congenital glaucoma.
Material And Methods: Thirty six eyes of 23 children at the age from 7 days to 6.5 years (mean 17.
Purpose: The evaluation of biomorphometric parameters of optic nerve head of the eyes in myopic anisometropia, to state if glaucoma similar changes described in adults were present.
Material And Methods: 17 children, 14 girls and 3 boys at the age from 7-18 years, mean 12.6 years with unilateral myopia of mean value 8.
Purpose: To evaluate the efficacy of trabeculectomy in the patients with juvenile glaucoma in the long-term follow-up.
Material And Methods: In 22 of 37 patients--41 trabeculectomies with basal iridectomy were performed. The age of children ranged from 6 to 18 years, mean 12.
Unlabelled: The aim of our research was to estimate the correlation between optic nerve head parameters examined with laser scanning ophthalmoscope and results of central, visual field (MD and PSD) in the youth and the evaluation the role of this correlation in juvenile glaucoma early diagnosis.
Material: Three groups of patients. Group I consisted of 32 eyes (16 children) with juvenile glaucoma in which trabeculectomy was performed.
Purpose: To demonstrate 3 cases with pediatric pseudophakia after cataract extraction as a complication of unilateral uveitis.
Material And Methods: The boys were at the age of 8, 11 and 15 years at the moment of surgery. Uveitis was monocular, the etiology unknown and clinically significant cataract was diagnosed after several months from the beginning of inflammation.
Purpose: To estimate the effectiveness of trabeculectomy performed in buphthalmic eyes.
Material And Methods: 42 eyes of 24 children, 14 boys and 10 girls. There were 18 children (32 eyes) operated on at the age from 7 days to 12 months (group I) and 6 patients (10 eyes) at the age from 3 to 7 years (group II) with primary congenital glaucoma.
The authors describe a case of patient with orbital large foreign body (glass) treated using Kronlein lateral orbitotomy.
View Article and Find Full Text PDFThe aim of congenital glaucoma treatment is to preserve visual function of children's eyes. There are three forms of congenital glaucoma: primary congenital glaucoma of infants, children and the youth, glaucoma in dysgenesis of anterior segment of the eyeballs and glaucoma in congenital systemic diseases. Pharmacotherapy is indicated during preparation for surgical treatment, as an adjunct following surgical procedures and as a protection of retinal and optic nerve function.
View Article and Find Full Text PDFThe aim of our research was to evaluate the optic nerve head parameters of children with juvenile glaucoma with the scanning laser ophthalmoscope from Laser Diagnostic Technologies Inc. The material consisted of 46 eyes of 25 children aged from 7 to 18 years. There were 18 glaucomatous eyes (I group) and 28 eyes without glaucoma (II group) as a control group.
View Article and Find Full Text PDFPurpose: We present our own results of treatment in corneal ulcerations with therapeutic contact lenses in 4 infants aged between 3 days to 5 weeks.
Material And Methods: Four patients (5 eyes) with deep corneal ulcerations of various origin were treated with soft contact lenses at the Clinic of Pediatric Ophthalmology in Katowice. All eyes received one type of the therapeutic lens.
Purpose: To evaluate the anatomical and functional state of eyeballs after cataract extraction in uveitis in children and to analyze the factors affecting visual outcome.
Material And Methods: Among 182 examined eyes with uveitis we have observed cataract in 22 eyeballs of 17 children (12%). Before operation in 72.
Unlabelled: The diagnosis of the open angle glaucoma in myopic eyes remains one of the major problems, as the changes of the optic head in myopia may be similar to glaucomatous changes. The aim of the study was to analyse biomorphometric parameters of the optic nerve head in myopic eyes with glaucoma with scanning laser ophthalmoscope from Laser Diagnostic Technologies Inc. There was 29 children examined and among them 12 children with glaucoma and myopia as a study group (I) and 17 children with myopia as a control group (II).
View Article and Find Full Text PDFBackground: The possibilities of using computer in physician's research work are presented as an example of statistical analysis of axial eyeball length in relation to the age in myopic children with low birthweight.
Material And Methods: The study group consisted of 100 children aged from 3 to 15 years, with birthweight from 580 to 2450 g, where in 180 eyes myopia ranging from -1.5 to -22.
Aim: The relation between myopia and birth weight of premature newborns was assessed in this study.
Material And Methods: There were 90 children (180 eyes) involved in the study, their birth weight ranged between 580 and 2450 g (mean 1698), and myopia ranged from -1.5 to -22.
Purpose: Analysis of etiological factors and functional assessment of the eyes.
Material And Methods: Optic disc hypoplasia was diagnosed in 43 children, aged 12 months--12 years, unilateral in 9 (20.9%).