Melatonin is produced by the pineal gland and plays a role in regulating circadian rhythm. It influences the physiologic processes, such as the activation of the immune system and the antioxidant function. Melatonin has been reported in the samples of patients with periodontitis.
View Article and Find Full Text PDFBackground: Respiratory syncytial virus vaccines first recommended for use during 2023 were efficacious against lower respiratory tract disease in clinical trials. Limited real-world data regarding respiratory syncytial virus vaccine effectiveness are available. To inform vaccine policy and address gaps in evidence from the clinical trials, we aimed to assess the effectiveness against respiratory syncytial virus-associated hospitalisations and emergency department encounters among adults aged at least 60 years.
View Article and Find Full Text PDFBackground: Malocclusion and lifestyle diseases like obesity can lead to poor oral hygiene and food stagnation, resulting in increased caries incidence.
Objectives: To evaluate the interrelationship of age, body mass index (BMI), occlusion, and dental decay in children aged between 5 and 14.
Methodology: Our study included 423 school students aged 5-14 visiting dental clinics.
Objectives: This study describes a robust and versatile method for decellularization of rat submandibular glands (SMGs).
Methods: Briefly, rat SMGs were harvested and subjected to perfusion cycles using an anionic detergent. Native and decellularized SMG tissues were subjected to histological analysis using hematoxylin and eosin (H&E) stain and immunohistochemical staining using Hoescht reagent.
Introduction: Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) is a chronic illness characterized by marked functional limitations and fatigue. Electronic health records can be used to estimate incidence of ME/CFS but may have limitations.
Methods: The authors used International Classification of Diseases (ICD) diagnosis codes to identify all presumptive cases of ME/CFS among 9- to 39-year-olds from 2006 to 2017.
Background And Objective: The most frequently seen intra-oral soft tissue is the gingiva. Most often, it is seen as coral-pink tissue that surrounds the neck of the teeth. Gingiva that encircles the tooth necks and covers the alveolar processes of the jaws is an intra-oral tissue that exhibits biomimetic features.
View Article and Find Full Text PDFSystemic lupus erythematosus (SLE) with oral desquamative lesions is one of the rare clinical entities. Periodontal disease and SLE display various mechanisms and possess a wide range of pathological characteristics. The tissue destruction mechanism of periodontitis and autoimmune diseases share similar pathways, and mounting reports studied the association between these two entities.
View Article and Find Full Text PDFThe risk of complications, and thus the quality of life, for elderly diabetic patients is greatly affected by inadequate blood glucose control. Examining how Type 2 diabetic patients(T2DM)' complication rates and overall satisfaction with health care professional care change in response to a goal-oriented patient centric health care professional intervention. One hundred people were analysed in this study.
View Article and Find Full Text PDFBackground: Evidence suggests that some infectious diseases, such as herpes zoster (HZ), are associated with elevated risk of subsequent dementia, while certain anti-viral medications are associated with lower risk. We sought to evaluate associations between HZ diagnosis and treatment with incident dementia in a large, retrospective matched cohort.
Methods: Using ICD-9 and ICD-10 diagnosis codes in electronic medical records, we identified members of Kaiser Permanente Northwest age 50 and older from 2000-2019 with a HZ diagnosis during this period.
Aim: Periodontitis is an inflammatory condition of the periodontium that is instigated by microbial biofilms developed on the teeth. The purpose of the study was to ascertain the vitamin D status of gingivitis and periodontitis patients while maintaining a healthy group as the control using simple low-cost chairside pre-coated with 25-OH Vitamin D antigen rapid test kits.
Materials And Methods: From outpatients visiting the college's periodontics clinics, a total of 101 patients were screened.
J Electromyogr Kinesiol
December 2023
Surface Electromyography (sEMG) signals are muscle activation signals, which has applications in muscle diagnosis, rehabilitation, prosthetics, and speech etc. However, they are known to be affected by noises such as Power Line Interference (PLI), motion artifacts etc. Currently, Empirical Mode Decomposition (EMD) and its modifications such as Ensemble EMD (EEMD), and Complementary EEMD (CEEMD) are used to decompose EMG into a series of Intrinsic Mode Functions (IMFs).
View Article and Find Full Text PDFBackground: Neutrophils continuously migrate into the oral cavity from various sources like gingival crevicular fluid and saliva both in health and in inflammation. The migration of the neutrophils into the various tissues and into the oral cavity occurs when the host microbial interplay tips the balance favoring the initiation of the inflammatory and immune reactions which depending on the amount of the microbial load results in the development of acute and chronic infections in the susceptible host.
Aim: The present study was designed to quantify and compare the oral salivary neutrophil levels in patients with gingivitis and chronic and aggressive periodontitis as well as in healthy controls, before and after scaling and root planing (SRP) and to compare the difference within the selected study groups.
Aim: The present cross-sectional observational study was conducted to evaluate the prevalence of halitosis among undergraduate university students at Riyadh Elm University, Riyadh, Saudi Arabia.
Materials And Methods: A survey of 301 participants who answered a questionnaire on their self-perceived halitosis was undertaken.
Results: The response rate was 35% (301/863).
Background: Gingival recession (GR) has become a common problem among patients. GR is associated with increased accumulation of plaque, root caries, abrasion and cervical wear, and dentinal hypersensitivity. The present study aimed to examine the correlation between gingival biotypes and the occurrence of GR.
View Article and Find Full Text PDFBackground: Dental caries is one of the most common chronic childhood diseases and is a cause of continuous discomfort through impaired function and esthetics. To control dental caries, the removal of plaque is of utmost importance, and that further necessitates the use of chemotherapeutic agents. Several side effects associated with chlorhexidine have stimulated the search for an alternative chemotherapeutic agent.
View Article and Find Full Text PDFMucormycosis is called as black fungus, which is caused by fungus belonged to Mucorales. If this fungus, effects healthy individuals it won't cause any serious complications, but it may cause life-threatening issues when Mucorales affects individuals who have low immunity. The mortality rate of black fungus is more than 50%, and it may also range till 100% if the individual is having any preexisting or chronic disease.
View Article and Find Full Text PDFBackground: Periodontitis and coronavirus disease (COVID-19) both exhibit an exaggerated inflammatory response as common traits. Given that periodontal diseases have been linked to respiratory illnesses like pneumonia, it is quite possible that periodontitis and COVID-19 are related. Therefore, the purpose of the current study was to ascertain whether the severity of COVID-19 and periodontal disease are related.
View Article and Find Full Text PDFAim: This study aimed to compare the efficacy of ozonated water mouth rinse over chlorhexidine mouth rinse against the accumulation of plaque in chronic gingivitis patients.
Materials And Methods: A total of 30 patients with chronic generalized gingivitis were choosen for the study. The duration of this study was 15 days and was divided into three groups.
Background: The gingival recession causes tooth sensitivity, poor esthetics, and tooth mobility in severe cases. Scientific documentation revealed effective root coverage (RC) and increased keratinized tissue heights acquired with the coronally advanced flap (CAF) for multiple recession defects.
Objectives: This research evaluates and compares the efficacy of CAF procedures with and without Type I collagen bio-absorbable membrane in guided tissue regeneration (GTR) in the treatment of Miller's Class I and II gingival recession.
Background: Probiotic organisms Lactobacillus reuteri UBLRU-87 and Bifidobacterium bifidum UBBB-55 were proven to be acting against the caries causing organisms.
Aims: This study aims to evaluate the influence of Lactobacillusreuteri, Bifidobacterium bifidum and their blend on Mutans streptococci count in the saliva of children, and also to appraise the sustainability of their action.
Materials And Methods: A randomized, double-blind and placebo-controlled study with 60 subjects (15 in each group) in 6-14 years of age group.
Purpose: This study sought to investigate the acceptance rate and associated factors of COVID-19 vaccines among dentists and dental students in seven countries.
Material And Methods: A structured questionnaire prepared and guided by the report of the SAGE Working Group on Vaccine Hesitancy was distributed among groups of dentists and dental students in seven countries across four continents.
Results: A total of 1527 subjects (850 dentists and 677 dental students) participated in this survey.
Mandibular prognathism combined with a retrognathic maxilla is a skeletal discrepancy that is difficult to correct. We report a case of a 25-year-old Saudi male patient with skeletal class-III malocclusion due to severe prognathic mandible who was referred to an orthodontist at Prince Sultan Military Medical City. Complete clinical examination, radiographic assessment, and study models revealed class-III malocclusion due to anteroposterior deficiency of the maxilla and severe prognathic mandible.
View Article and Find Full Text PDFNormally root canal-treated teeth are covered with crowns to prevent fracture, which becomes challenging in cases where the tooth is extensively damaged. In such instances, various restorative methods such as post-core and endocrowns have been in use. The former methodology in recent times is being discouraged owing to impending tooth weakening.
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