Change in Clinical Risk Factors During Stay and Treatment in a Penitentiary Psychiatric Center.

This study examines the changes in clinical risk factors among individuals treated in Dutch Penitentiary Psychiatric Centers (PPCs). Using data from 874 patients with diverse psychiatric disorders, clinical risk factors were assessed at admission and discharge. Slight but significant improvements were observed in most risk factors, particularly psychotic symptoms, over an average stay of approximately 6 months.

Central tendency and serial dependence in vestibular path integration.

Path integration, the process of updating one's position using successive self-motion signals, has previously been studied with visual distance reproduction tasks in which optic flow patterns provide information about traveled distance. These studies have reported that reproduced distances show two types of systematic biases: central tendency and serial dependence. In the present study, we investigated whether these biases are also present in vestibular path integration.

Building climate resilience: awareness of climate change adaptation in German outpatient medical practices.

Background: Climate change is seen as the biggest health threat of the twenty-first century. Making outpatient medical practices resilient is therefore crucial to protect vulnerable groups and maintain quality of care. Awareness is a precondition for action.

Smart Farm Security by Combining IoT Sensor Network and Virtualized Mycelium Network.

In today's world, merging sensor-based security systems with contemporary principles has become crucial. As we witness the ever-growing number of interconnected devices in the Internet of Things (IoT), it is imperative to have robust and trustworthy security measures in place. In this paper, we examine the idea of virtualizing the communication infrastructure for smart farming in the context of IoT.

Optimizing Antibiotic Prescribing for Acute Respiratory Tract Infections in German Primary Care: Results of the Regional Intervention Study CHANGE-3 and the Nested cRCT.

Within primary care, acute respiratory tract infections (ARTIs) are the most common reason for prescribing antibiotics. The aim of the CHANGE-3 study was to investigate how antibiotic prescribing for non-complicated ARTIs can be reduced to a reasonable level. The trial was conducted as a prospective study consisting of a regional public awareness intervention in two regions of Germany and a nested cluster randomised controlled trial (cRCT) of a complex implementation strategy.

IoT and Deep Learning-Based Farmer Safety System.

Farming is a fundamental factor driving economic development in most regions of the world. As in agricultural activity, labor has always been hazardous and can result in injury or even death. This perception encourages farmers to use proper tools, receive training, and work in a safe environment.

Domestic Violence During the Corona Pandemic: A Comparison of Pre-Pandemic and Pandemic Incidents of Domestic Violence in the Netherlands.

There is a widespread fear that the measures as a consequence of the worldwide corona pandemic have led to a significant increase in domestic violence and child abuse. The current study uses criminal files from all incidents of domestic violence that were reported to the police in a relatively large city in the Netherlands during 3.5 months before the pandemic and the first 3.

[Acute respiratory tract infections and antibiotic prescriptions: What are patients' expectations?].

Introduction: The use of antibiotics in human medicine is partly responsible for the global increase in antibiotic resistance. Significant reductions in antibiotic prescribing were realised through educational campaigns, communication training and prescribing feedback. Based on data from the cluster-randomised CHANGE-3 trial, the present analysis focuses on the question of patient expectations for an antibiotic in acute respiratory infections.

Natural statistics of head roll: implications for Bayesian inference in spatial orientation.

We previously proposed a Bayesian model of multisensory integration in spatial orientation (Clemens IAH, de Vrijer M, Selen LPJ, van Gisbergen JAM, Medendorp WP. J Neurosci 31: 5365-5377, 2011). Using a Gaussian prior, centered on an upright head orientation, this model could explain various perceptual observations in roll-tilted participants, such as the subjective visual vertical, the subjective body tilt (Clemens IAH, de Vrijer M, Selen LPJ, van Gisbergen JAM, Medendorp WP.

[Acute respiratory tract infections and antibiotic prescriptions: What are patients' expectations?].

Introduction: The use of antibiotics in human medicine is partly responsible for the global increase in antibiotic resistance. Significant reductions in antibiotic prescribing were realised through educational campaigns, communication training and prescribing feedback. Based on data from the cluster-randomised CHANGE-3 trial, the present analysis focuses on the question of patient expectations for an antibiotic in acute respiratory infections.

Implementing a Hand Gesture Recognition System Based on Range-Doppler Map.

There have been several studies of hand gesture recognition for human-machine interfaces. In the early work, most solutions were vision-based and usually had privacy problems that make them unusable in some scenarios. To address the privacy issues, more and more research on non-vision-based hand gesture recognition techniques has been proposed.

An extended hesitant fuzzy set using SWARA-MULTIMOORA approach to adapt online education for the control of the pandemic spread of COVID-19 in higher education institutions.

The world has been challenged since late 2019 by COVID-19. Higher education institutions have faced various challenges in adapting online education to control the pandemic spread of COVID-19. The present study aims to conduct a survey study through the interview and scrutinizing the literature to find the key challenges.

Biocompatible, Crystalline, and Amorphous Bismuth-Based Metal-Organic Frameworks for Drug Delivery.

The synthetic flexibility of metal-organic frameworks (MOFs) with high loading capacities and biocompatibility makes them ideal candidates as drug delivery systems (DDSs). Here, we report the use of CAU-7, a biocompatible bismuth-based MOF, for the delivery of two cancer drugs, sodium dichloroacetate (DCA) and α-cyano-4-hydroxycinnamic acid (α-CHC). We achieved loadings of 33 and 9 wt % for DCA and α-CHC, respectively.

Time course of the subjective visual vertical during sustained optokinetic and galvanic vestibular stimulation.

The brain is thought to use rotation cues from both the vestibular and optokinetic system to disambiguate the gravito-inertial force, as measured by the otoliths, into components of linear acceleration and gravity direction relative to the head. Hence, when the head is stationary and upright, an erroneous percept of tilt arises during optokinetic roll stimulation (OKS) or when an artificial canal-like signal is delivered by means of galvanic vestibular stimulation (GVS). It is still unknown how this percept is affected by the combined presence of both cues or how it develops over time.

Contributions of optostatic and optokinetic cues to the perception of vertical.

While it has been well established that optostatic and optokinetic cues contribute to the perception of vertical, it is unclear how the brain processes their combined presence with the nonvisual vestibular cues. Using a psychometric approach, we examined the percept of vertical in human participants ( = 17) with their body and head upright, presented with a visual frame tilted at one of eight orientations (between ±45°, steps of 11.25°) or no frame, surrounded by an optokinetic roll-stimulus (velocity =  ±30°/s or stationary).

Weighted Visual and Vestibular Cues for Spatial Updating During Passive Self-Motion.

When walking or driving, it is of the utmost importance to continuously track the spatial relationship between objects in the environment and the moving body in order to prevent collisions. Although this process of spatial updating occurs naturally, it involves the processing of a myriad of noisy and ambiguous sensory signals. Here, using a psychometric approach, we investigated the integration of visual optic flow and vestibular cues in spatially updating a remembered target position during a linear displacement of the body.

Causal inference for spatial constancy across whole body motion.

The brain uses self-motion information to internally update egocentric representations of locations of remembered world-fixed visual objects. If a discrepancy is observed between this internal update and reafferent visual feedback, this could be either due to an inaccurate update or because the object has moved during the motion. To optimally infer the object's location it is therefore critical for the brain to estimate the probabilities of these two causal structures and accordingly integrate and/or segregate the internal and sensory estimates.

Psychophysical Evaluation of Sensory Reweighting in Bilateral Vestibulopathy.

Perception of spatial orientation is thought to rely on the brain's integration of visual, vestibular, proprioceptive, and somatosensory signals, as well as internal beliefs. When one of these signals breaks down, such as the vestibular signal in bilateral vestibulopathy, patients start compensating by relying more on the remaining cues. How these signals are reweighted in this integration process is difficult to establish, since they cannot be measured in isolation during natural tasks, are inherently noisy, and can be ambiguous or in conflict.

A multi-purpose reaction cell for the investigation of reactions under solvothermal conditions.

A new versatile and easy-to-use remote-controlled reactor setup aimed at the analysis of chemical reactions under solvothermal conditions has been constructed. The reactor includes a heating system that can precisely control the temperature inside the reaction vessels in a range between ambient temperature and 180 °C. As reaction vessels, two sizes of commercially available borosilicate vessels (V = 5 and 11 ml) can be used.

Synthesis, functionalisation and post-synthetic modification of bismuth metal-organic frameworks.

Two new bismuth metal-organic frameworks (Bi-MOFs) were discovered using high throughput experiments employing bismuth(iii) nitrate pentahydrate and triazine-2,4,6-triyl-tribenzoic acid (HTATB). The reaction was carried out for long reaction times (∼5 d) in a water/DMF-mixture and resulted in the formation of [Bi(O)(OH)(TATB)]·HO (denoted as CAU-35). By switching to short reaction times and a methanol/DMF-mixture as the solvent, an analogue of CAU-7-BTB with the composition [Bi(TATB)]·DMF·6HO (denoted as CAU-7-TATB) was obtained.

Decisions in motion: vestibular contributions to saccadic target selection.

The natural world continuously presents us with many opportunities for action, and thus a process of target selection must precede action execution. While there has been considerable progress in understanding target selection in stationary environments, little is known about target selection when we are in motion. Here we investigated the effect of self-motion signals on saccadic target selection in a dynamic environment.