Publications by authors named "Kopano Valerie Masete"
Article Synopsis
- Traditional cell line monolayers have been the standard for studying epithelial barrier and transport, but 3D intestinal organoids are emerging as a better model for studying these functions.
- Researchers developed human duodenum-derived organoid monolayers that don't require a gelatinous matrix for anchorage, which could hinder diffusion.
- The new organoid monolayers effectively replicate the duodenum’s functions and composition, showing improved models for studying transport mechanisms without relying on animal-derived materials.
