Publications by authors named "Kopano Valerie Masete"

Article Synopsis
  • Traditional cell line monolayers have been the standard for studying epithelial barrier and transport, but 3D intestinal organoids are emerging as a better model for studying these functions.
  • Researchers developed human duodenum-derived organoid monolayers that don't require a gelatinous matrix for anchorage, which could hinder diffusion.
  • The new organoid monolayers effectively replicate the duodenum’s functions and composition, showing improved models for studying transport mechanisms without relying on animal-derived materials.
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