Heterogeneity by global and textural feature analysis in F-18 FP-CIT brain PET images for diagnosis of Parkinson's disease.

Background: The quantification of heterogeneity for the striatum and whole brain with F-18 FP-CIT PET images will be useful for diagnosis. The index obtained from texture analysis on PET images is related to pathological change that the neuronal loss of the nigrostriatal tract is heterogeneous according to the disease state. The aim of this study is to evaluate various heterogeneity indices of F-18 FP-CIT PET images in the diagnosis of Parkinson's disease (PD) patients and to access the diagnostic accuracy of the indices using machine learning (ML).

Restoration of amyloid PET images obtained with short-time data using a generative adversarial networks framework.

Our purpose in this study is to evaluate the clinical feasibility of deep-learning techniques for F-18 florbetaben (FBB) positron emission tomography (PET) image reconstruction using data acquired in a short time. We reconstructed raw FBB PET data of 294 patients acquired for 20 and 2 min into standard-time scanning PET (PET) and short-time scanning PET (PET) images. We generated a standard-time scanning PET-like image (sPET) from a PET image using a deep-learning network.

Osteosarcoma of talus with heterotopic ossifications and lung metastases.

Osteosarcoma is the most common malignant bone tumor and is known to occur mainly in the metaphyses of long bones. However, a few cases of osteosarcoma in talus have been reported in older patients. We experienced an osteosarcoma of an 80-year-old male patient with a talus which is rarely reported and evaluated disease patterns with four different imaging modalities.

Assessment of brain beta-amyloid deposition in transgenic mouse models of Alzheimer's disease with PET imaging agents F-flutemetamol and F-florbetaben.

Background: Although amyloid beta (Aβ) imaging is widely used for diagnosing and monitoring Alzheimer's disease in clinical fields, paralleling comparison between F-flutemetamol and F-florbetaben was rarely attempted in AD mouse model. We performed a comparison of Aβ PET images between F-flutemetamol and F-florbetaben in a recently developed APPswe mouse model, C57BL/6-Tg (NSE-hAPPsw) Korl.

Results: After an injection (0.

Enzymatic Properties of Two Calcium-stimulated ATPases in the Neutral and Acidic pH Regions Found in the Membrane Fraction of Human Milk.

Two calcium-stimulated ATPases at optimal pH values of 5.0 and 7.0, which are designated as acid and neutral Ca(2+) -ATPase, respectively, were found in the membrane fraction of human milk, and their enzymatic properties were studied.