Feasibility of Setting the Tidal Volume Based on End-Expiratory Lung Volume: A Pilot Clinical Study.

Objectives: To assess the feasibility of setting the tidal volume (TV) as 25% of the actual aerated lung volume (rather than on ideal body weight) in patients with Acute Respiratory Distress Syndrome (ARDS).

Design: Physiologic prospective single-center pilot study.

Setting: Medical ICU specialized in the care of patients with ARDS.