Publications by authors named "Konstantsa Neykova"

Objectives: The aim of our study was to investigate the interrelations of symptoms, clinical outcomes and treatment regimens in pregnant women, diagnosed with myasthenia gravis and superimposed COVID-19 infection.

Methods: We conducted an observational retrospective study between August, 2020 and July, 2021. Five patients with preexisting MG and superimposed COVID- infection were included in our study.

View Article and Find Full Text PDF

Introduction: Various factors related to an "" fertilization (IVF) procedure may influence the rate of small for gestational age (SGA) newborns in such pregnancies.

Aim: The aim of the study was to determine neonatal SGA incidence in singleton IVF pregnancies compared to spontaneous ones.

Materials And Methods: We conducted both a prospective and a retrospective study within the period of January 2013-December 2017, which included 336 patients with a singleton IVF pregnancy at the time of delivery - the study group (SG), and 493 women with a spontaneous conception - the control group (CG).

View Article and Find Full Text PDF

Human implantation is a highly complex and multifactorial process. Successful implantation requires the presence of a healthy embryo, a receptive endometrium, and a synchronized molecular dialogue between the two, as well as immune tolerance/protection from the host. The endometrial receptivity refers to a hormonally limited period in which the endometrial tissue acquires a transient functional status allowing blastocyst implantation and pregnancy initiation.

View Article and Find Full Text PDF

Objectives: To analyze the recurrence rate of placenta-mediated diseases (PMDs) such as preeclampsia (PE) and/or intrauterine growth restriction (IUGR), intrauterine fetal death (IUFD), and placental abruption (PA) in high-risk patients on antithrombotic therapy (AT) because of a previous obstetrical history for such complications.

Methods: The study group (SG) included 150 patients to whom either 100 mg of aspirin or low-molecular weight heparin (LMWH) was administered due to a previous history of PMDs. The AT in the SG was started before 16 gestational weeks (g.

View Article and Find Full Text PDF