Publications by authors named "Konstantinos Xynos"

Article Synopsis
  • The study investigates trends in stroke incidence and fatality rates in Arcadia, Greece, over three time periods: 1993-1995, 2004, and 2015-2016.
  • Out of 1315 first-ever stroke cases, the research reveals that the age-standardized incidence rate decreased from 252 per 100,000 person-years in 1993/1995 to 211 in 2015/2016, indicating a 16% decline.
  • Additionally, the 28-day case fatality rate also showed improvement, decreasing by 28% over the same period, suggesting better outcomes and healthcare strategies for stroke management in the region.
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Background: In patients with chronic kidney disease (CKD), impaired renal function leads to decreased vitamin D levels, which causes an increase in parathyroid hormone (PTH) production and contributes to the development of secondary hyperparathyroidism (SHPT). This may result in adverse clinical effects such as bone disorders, vascular calcification, cardiovascular disease, and increased mortality. Current treatment practices and associated outcomes with active vitamin D treatment in patients with CKD were reviewed with the objective to assess parameters (such as PTH and serum calcium levels) that may be used to define the failure of vitamin D treatment.

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Background: Chronic Kidney Disease (CKD) is a relatively common condition not only associated with increased morbidity and mortality but also fuelling End Stage Renal Disease (ESRD). Among developed nations, Greece has one of the highest ESRD incidence rates, yet there is limited understanding of the epidemiology of earlier stages of CKD.

Methods: Cross-sectional survey of pre-dialysis CKD outpatients in nephrology clinics in the National Health Care system between October 2009 and October 2010.

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Background: On June 11th, 2009 the World Health Organization (WHO) declared the first influenza pandemic of the 21st century. Data regarding the clinical characteristics and course of this viral infectious disease are still being assessed. The aim of this study was to investigate and compare the possible differences in clinical course and outcome between H1N1-positive [H1N1(+)] and negative [H1N1(-)] patients.

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Objective: It has been reported that hypothyroidism is associated with better survival in elderly persons. We investigated possible associations of thyroid status with clinical outcome in patients with acute stroke.

Design: Retrospective analysis.

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