Publications by authors named "Konstantinos Roufas"
Long-term serial changes in platelet activation indices following sirolimus elution and bare metal stent implantation in patients with stable coronary artery disease.
Maria Marketou George E Kochiadakis Aikaterini Giaouzaki Katerini Sfiridaki Stelios Petousis Konstantinos Roufas
Hellenic J Cardiol
March 2018
Background: Platelet activation is crucial in the development of stent thrombosis following percutaneous coronary intervention (PCI). We carried out a long-term assessment of multiple factors implicated in the thrombotic process and monitored markers of platelet activation after the implantation of sirolimus-eluting stents (SES) in patients with stable coronary artery disease (CAD). Additionally, we compared these findings with those after bare-metal stent (BMS) implantation.
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- Fabry disease is a rare genetic disorder linked to the X chromosome, caused by a lack of the enzyme alpha-galactosidase A, leading to the buildup of certain fats in the body.
- The pN215S mutation typically results in a milder form of the disease, primarily affecting the heart, but it may also cause generalized symptoms in some patients.
- A case study highlights a male patient with the pN215S mutation who experienced a worsening of kidney function (proteinuria) that improved with higher doses of enzyme replacement therapy, emphasizing the need for personalized treatment strategies.