Purpose: During the past two years, in most institutions worldwide, educational activities were remodeled for remote delivery, due to the COVID-19 pandemic. The purpose of this study is to assess the effects of two-year distance learning on the physical activity and musculoskeletal health of university students.
Methods: This was a national, cross-sectional study using data collected via an online questionnaire distributed through university communication platforms, which included questions on online education routines, musculoskeletal health, and physical activity of university students.
Sclerosing mesenteritis is primarily diagnosed through histologic and radiologic evaluation; however, only a few works provide a systematic description using MRI. This work presents the case of a 68-year-old male, who was admitted for a routine cholecystectomy. Intraoperativly, a large mass was identified dislocating the abdominal viscera.
View Article and Find Full Text PDFHeat shock proteins (hsps) are induced by stressful stimuli and have been shown to protect cells and organs from such stresses both in vitro and in vivo. Because of this, mildly stressful stimuli, sufficient to induce hsp over-expression can protect against a subsequent more severe stress. In cells from aged individuals, however, no hsp induction is observed upon exposure to stress and no protective effect of a mild stress is observed.
View Article and Find Full Text PDFPeripheral blood mononuclear cells (PBMCs) represent a significant target for gene delivery both for therapeutic and experimental purposes. Thus far however, it has proved difficult to develop vectors capable of high efficient gene delivery to unstimulated PBMCs. We have tested a range of different vectors derived from herpes simplex virus (HSV) which differ in their degree of disablement in terms of their gene delivery efficiency to unstimulated human PBMCs and ability to deliver a reporter gene.
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