Publications by authors named "Konosuke Sato"
Article Synopsis
- Mutations in certain genes are associated with frontotemporal lobar degeneration (FTLD), but whether these mutations lead to gain or loss of function is still debated.
- Research using Drosophila flies showed that knocking down the TER94 gene, similar to the human gene VCP/p97, resulted in severe health issues like early death and changes in brain structure, which were not restored by a known mutant version of the gene.
- The study implies that the issues caused by TER94 knockdown are due to loss-of-function effects, particularly affecting cell proliferation and leading to the loss of another protein, TBPH, from cell nuclei.
Luminescence thermometry is a non-contact method that can measure surface temperatures and the temperature of the area where the fluorescent probe is located, allowing temperature distribution visualizations with a camera. Ratiometric fluorescence thermometry, which uses the intensity ratio of fluorescence peaks at two wavelengths with different fluorescence intensity dependencies, is an excellent method for visualizing temperature distributions independent of the fluorophore spatial concentration, excitation light intensity and absolute fluorescence intensity. Herein, Nd/Yb/Er-doped YO nanomaterials with a diameter of 200 nm were prepared as phosphors for temperature distribution measurement of fluids at different temperatures.
View Article and Find Full Text PDFSignificance: Determining the extent of gastric cancer (GC) is necessary for evaluating the gastrectomy margin for GC. Additionally, determining the extent of the GC that is not exposed to the mucosal surface remains difficult. However, near-infrared (NIR) can penetrate mucosal tissues highly efficiently.
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