Publications by authors named "Konoha Tomono-Duval"
Article Synopsis
- The study focuses on the role of a specific long noncoding RNA, slincR, in how organisms respond to environmental toxins, specifically the compound TCDD which binds to the aryl hydrocarbon receptor (AHR).
- Researchers created a CRISPR-Cas9 mutant line of zebrafish with an altered slincR gene to investigate its biological functions, revealing that these mutant fish displayed increased sensitivity to TCDD, affecting their morphology and behavior.
- The findings indicate that the mutation in slincR disrupts metabolic pathways and cartilage development, and impairs the regenerative ability of the zebrafish, highlighting the lncRNA's crucial role in development and toxicological responses.
