Depression and Anxiety Among COVID-19 Patients Admitted to a "Red Zone" Intensive Care Unit: Do the Factors of Self-Awareness of Somatic Health, Anxiety, and Depression Contribute to the Course of Sars-Cov-2 Infection?

Background: The prevalence of depressive disorders in the general population increased significantly during the COVID-19 pandemic. The aim of this study is to examine the relationship between history of anxiety and depressive disorders and COVID-19 outcome, hospitalization and severity of anxiety and depression, and whether such relationships are explicable by direct impact of the disease.

Subjects And Methods: We conducted a questionnaire survey among 98 inpatients in the Department of Infectious Diseases of the Clinics of Samara State Medical University.

Isolation and Characterization of 1-Hydroxy-2,6,6-trimethyl-4-oxo-2-cyclohexene-1-acetic Acid, a Metabolite in Bacterial Transformation of Abscisic Acid.

We report the discovery of a new abscisic acid (ABA) metabolite, found in the course of a mass spectrometric study of ABA metabolism by the rhizosphere bacterium sp. P1Y. Analogue of (+)-ABA, enriched in tritium in the cyclohexene moiety, was fed in bacterial cells, and extracts containing radioactive metabolites were purified and analyzed to determine their structure.

Structure-Functional Characteristics of the Svx Protein-The Virulence Factor of the Phytopathogenic Bacterium .

The Svx proteins are virulence factors of phytopathogenic bacteria of the genus. The specific functions of these proteins are unknown. Here we show that most of the phytopathogenic species of , , and genera have genes encoding Svx proteins, as well as some plant-non-associated species of different bacterial genera.

Transcriptomic data of subsp. serovar Typhimurium str. 14028S treated with novobiocin.

In enteric bacteria, DNA supercoiling is highly responsive to environmental conditions. Host specific features of environment serve as cues for the expression of genes required for colonization of host niches via changing supercoiling [1]. It has been shown that substitution at position 87 of GyrA of str.

Dataset for transcriptome analysis of abscisic acid degrading bacterium sp. P6W.

Plant growth-promoting rhizobacteria (PGPR) improve plant productivity and stress resistance. The mechanisms involved in plant-microbe interactions include the modulation of plant hormone status. The sp.

Complete Genome Sequence of Abscisic Acid-Metabolizing Rhizobacterium sp. Strain P1Y.

Mechanisms of microbial catabolism of phytohormone abscisic acid (ABA) are still unknown. Here, we report the complete genome sequence of ABA-utilizing sp. strain P1Y, isolated from the rice ( L.

NMR solution structure of the RED subdomain of the Sleeping Beauty transposase.

DNA transposons can be employed for stable gene transfer in vertebrates. The Sleeping Beauty (SB) DNA transposon has been recently adapted for human application and is being evaluated in clinical trials, however its molecular mechanism is not clear. SB transposition is catalyzed by the transposase enzyme, which is a multi-domain protein containing the catalytic and the DNA-binding domains.

The folding of the specific DNA recognition subdomain of the sleeping beauty transposase is temperature-dependent and is required for its binding to the transposon DNA.

The reaction of DNA transposition begins when the transposase enzyme binds to the transposon DNA. Sleeping Beauty is a member of the mariner family of DNA transposons. Although it is an important tool in genetic applications and has been adapted for human gene therapy, its molecular mechanism remains obscure.

[Self-association and secondary structure of beta-casein].

The secondary structure alterations, accompanying isothermal and temperature guided beta-casein micellization have been studied by dynamic light scattering, circular dichroism and Fourier transform infrared spectroscopy techniques. Micelle formation induced by increase of protein concentration at constant temperature is accompanied by the formation of scanty number of additional peptide hydrogen bonds, preliminary assigned to intraprotein beta-structure. Heating results in more pronounced but qualitatively different changes consisted in dehydration of peptide groups and disruption of polyproline II helix segments with subsequent conversion to random and beta-turns.

Supramolecular design of biocompatible nanocontainers based on amphiphilic derivatives of a natural compound isosteviol.

Two diterpenoid surfactants with ammonium head groups and bromide (S1) or tosylate (S2) counterions have been synthesized. Exploration of these biomimetic species made it possible to demonstrate that even minor structural changes beyond their chemical nature may dramatically affect their solution behavior. While their aggregation thresholds differ inconsiderably, morphological behavior and affinity to lipid bilayer are strongly dependent on the counterion nature.

[Chaperone-like activity of beta-casein and thermal stability of alcohol dehydrogenase].

To elucidate the correlation of structural peculiarities of beta-casein and their chaperon-like activity the modified forms of the protein (with cysteinyl residues introduced in polypeptide chain) were investigated. The aggregation of native and recombinant beta-caseins was studied as well as their chaperon-like activity towards alcohol dehydrogenase thermal aggregation. It was shown that physico-chemical and chaperone-like properties ofdimeric and oligomeric forms ofbeta-casein (which formation is due to intermolecular disulfide bonds) differ significantly from monomeric forms.

[Compatibility of the F-like plasmid FB1drd with standard F-group plasmids in E. coli K12 strains].

Compatibility of depressed F-like plasmid FB1drd integrated into E. coli K12 cell chromosome with standard plasmids of FI-FVI compatibility groups was studied. The results obtained show that such plasmids can stably coexist in the same cell with plasmid FB1drd.