Hydrogen storage in a sandwich structure by assembly of BNs and MOFs.

Hybrid NUS-8/BNs with a sandwich-like structure were synthesized by layered h-BNs and MOF-NUS-8 assembly. Thanks to the more abundant exposed binding sites and partial ionic bonding properties of BN, the NUS-8/BN exhibits greatly improved H adsorption capacity, which is 1.7 times that of h-BN nanosheets.

Associations of total protein, albumin, and globulin with insulin resistance: an NHANES study.

Objective: Insulin resistance (IR) is a well-established major risk factor for type 2 diabetes mellitus, nonalcoholic fatty liver disease, and atherosclerotic cardiovascular disease. Previous studies have shown an association between increased serum albumin (ALB) levels and the risk of IR. However, there is a lack of studies simultaneously evaluating the association of total protein (TP), ALB, and globulin (GLB) with IR.

Pyridalthiadiazole-Based Molecular Chromophores for Defect Passivation Enables High-Performance Perovskite Solar Cells.

Passivation of defects at the surface and grain boundaries of perovskite films has become one of the most important strategies to suppress nonradiative recombination and improve optoelectronic performance of perovskite solar cells (PSCs). In this work, two conjugated molecules, abbreviated as CPT and SiPT, are designed and synthesized as the passivator to enhance both efficiency and stability of PSCs. The CPT and SiPT contain pyridalthiadiazole (PT) units, which can coordinate with undercoordinated Pb at the surface and grain boundaries to passivate the defects in perovskite films.

DRCTdb: disease-related cell type analysis to decode cell type effect and underlying regulatory mechanisms.

Understanding the molecular mechanisms underlying genetic diseases is challenging due to environmental and genetic factors. Genome-wide association studies (GWAS) have identified numerous genetic loci, but their functional implications are largely unknown. Single-cell multiomics sequencing has emerged as a powerful tool to study disease-specific cell types and their relationship with genetic variants.

Precision matters: the value of PET/CT and PET/MRI in the clinical management of cervical cancer.

The incidence of cervical cancer has been increasing recently, becoming an essential factor threatening patients' health. Positron emission computed tomography (PET/CT) and positron emission tomography/magnetic resonance imaging (PET/MRI) are multimodal molecular imaging methods that combine functional imaging (PET) and anatomical imaging (CT) with MRI fusion technology. They play an important role in the clinical management of patients with cervical cancer.

Electrochemiluminescence immunoassay system based on PCN-224-Mn and gold-platinum bimetallic nanoflowers for sensitive detection of ochratoxin A.

In this work, a novel Electrochemiluminescence Immunosensor was constructed using PCN-224-Mn and gold-platinum nanoflowers (AuPt NFs) for the ultrasensitive detection of ochratoxin A (OTA). PCN-224 modified with Mn (II) was synthesized as a probe material. The interaction efficiency of PCN-224 with SO was also greatly improved.

[Stabilization of Cd-contaminated Soil with Thiol-modified Biochar and Response of Soil Microorganisms].

To explore the stabilization effect of livestock manure biochar on Cd-contaminated soil and its impact on the soil environment, a pot experiment was conducted to investigate the stabilization efficiency of cattle manure-biochar （BC） and thiol-modified biochar （SBC） on Cd in soil and their effect on the soil properties and microbial community. The structural equation model （SEM） was used to analyze the effect pathways of BC and SBC on the soil microbial community. The results showed that BC and SBC increased soil pH, available potassium, available phosphorus, and organic matter content but decreased soil available nitrogen content compared with those in CK.

Enhanced Intramolecular Hole Transfer in Block Copolymer Enables >15% and Operational Stable Single-Material-Organic Solar Cells.

Recent studies on narrow bandgap all-conjugated block copolymer (BCP) single-material-organic solar cells (SMOSCs) have made unprecedented progress in power conversion efficiency (PCE); however, it still lacks understanding of the structure-property relationship in these highly mixed materials. Herein, the impact of different synthetic protocols (direct synthesis (d-BCP) versus sequential synthesis (s-BCP)) is first investigated on the relevant photovoltaic properties. Targeting the same BCP, namely PBDB-T-b-PYIT, it is found that the change in polymerization reaction leads to quite different optical and transport properties.

Continuous ketone monitoring: Exciting implications for clinical practice.

Diabetic ketoacidosis (DKA) is a life-threatening complication usually affecting people with type 1 diabetes (T1D) and, less commonly, people with type 2 diabetes. Early identification of ketosis is a cornerstone in DKA prevention and management. Current methods for ketone measurement by people with diabetes include capillary blood or urine testing.

Management of Clavicle Implant Failure With Olecranon Bone Graft: A Case Report.

Bone grafts have been important treatment tools in reconstructive orthopaedic surgery for years for traumatic osseous defects, defects resulting from resection of bone tumours, arthrodesis, and osteotomy procedures. We used an autologous olecranon bone graft to fill the bone gap due to fracture comminution in a patient with right clavicle implant failure. A 21-year-old male initially underwent primary fixation with a clavicle locking plate for a comminuted middle-third right clavicle fracture.

Tandem Electroreduction of Nitrate to Ammonia Using a Cobalt-Copper Mixed Single-Atom/Cluster Catalyst with Synergistic Effects.

Electrochemical conversion of waste nitrate (NO ) to ammonia (NH) for environmental applications, such as carbon-neutral energy sources and hydrogen carriers, is a promising alternative to the energy-intensive Haber-Bosch process. However, increasing the energy efficiency is limited by the high overpotential and selectivity. Herein, a Co─Cu mixed single-atom/cluster catalyst (Co─Cu SCC) is demonstrated-with well-dispersed Co and Cu active sites anchored on a carbon support-that delivers high NH Faradaic efficiency of 91.

Cochlear implantation in a familial rare syndromic ossification-related deafness and literature review.

Background: Kenny-Caffey Syndrome type 2 (KCS2) is a genetic disease affecting bone metabolism. However, cochlear implantation (CI) results have yet to be published in detail.

Objective: This study presents the gene, clinical characteristics, surgical outcomes, and literature review of 2 patients with sensorineural hearing loss related to KCS2.

Metal-N Coordination in Lithium-Sulfur Batteries: Inhibiting Catalyst Passivation.

Lithium-sulfur (Li-S) batteries exhibit great potential as the next-generation energy storage techniques. Application of catalyst is widely adopted to accelerate the redox kinetics of polysulfide conversion reactions and improve battery performance. Although significant attention has been devoted to seeking new catalysts, the problem of catalyst passivation remains underexplored.

A rapid real-time PCR assay for detecting Microdochium paspali causing sparse leaf patch on seashore paspalum and in environmental samples.

Background: Sparse leaf patch (SLP) is one of the most significant diseases affecting seashore paspalum (Paspalum vaginatum Sw.), caused by Microdochium paspali. Fast and accurate detection of this pathogen is crucial for effective disease management.

Formation of thermal-induced microgels from soy protein hydrolysates: Effects of selective proteolysis on glycinin/β-conglycinin.

This study explored the impact of selective proteolysis on the formation of thermally induced soy protein microgels. Glycinin hydrolysate (GH) and β-conglycinin hydrolysate (CH) were obtained by subjecting soy protein isolate to selective proteolysis for different hydrolysis time (10-90 min), as confirmed by SDS-PAGE. In the early stages of hydrolysis, free sulfhydryl, surface hydrophobicity, storage modulus (G') and loss modulus (G″) of GH and CH increased, which enhanced their gelling potential.

Acetylation of TIR domains in the TLR4-Mal-MyD88 complex regulates immune responses in sepsis.

Activation of the Toll-like receptor 4 (TLR4) by bacterial endotoxins in macrophages plays a crucial role in the pathogenesis of sepsis. However, the mechanism underlying TLR4 activation in macrophages is still not fully understood. Here, we reveal that upon lipopolysaccharide (LPS) stimulation, lysine acetyltransferase CBP is recruited to the TLR4 signalosome complex leading to increased acetylation of the TIR domains of the TLR4 signalosome.

CTBP1 links metabolic syndrome to polycystic ovary syndrome through interruption of aromatase and SREBP1.

Some patients with polycystic ovarian syndrome (PCOS) suffered from metabolic syndrome (MetS) including dyslipidemia, hyperinsulinism, but the underlying mechanism is unclear. Although C-terminal Binding Protein 1 (CTBP1) is a transcriptional co-repressor frequently involved in hormone secretion disorders and MetS-associated diseases, the role of CTBP1 in PCOS is rarely reported. In the present study, we found that CTBP1 expression was significantly elevated in primary granulosa cells (pGCs) derived from the PCOS with MetS patients and was positively associated with serum triglyceride, but negatively correlated with serum estradiol (E2) or high-density lipoprotein.