Publications by authors named "Kong Qing-nuan"
Cardiovasc Pathol
May 2011
Article Synopsis
- - Hypertrophic cardiomyopathy (HCM) can cause sudden death due to arrhythmias, potentially linked to changes in the pacemaker current I(f) and specific ion channels known as HCN1-4.
- - A study compared left ventricular tissue from four HCM patients and six healthy individuals, using a technique called RT-PCR to measure HCN4 mRNA levels.
- - Results showed significantly higher levels of HCN4 mRNA in HCM hearts, indicating that increased expression of this gene may contribute to the dangerous arrhythmias seen in HCM patients.
