[Chronic granulomatous disease (in a 2-month-old infant)].

The paper describes a severe form of chronic granulomatous disease with onset in the neonatal period; the case presented is a 2-month-old male infant, coming from a family in which hid older brother died with signs of the same illness. The disease is rare. This is the second report in our literature.

[Familial leukemia].

Occurrence of familial leukaemia confirms the influence of genetic factors in the appearance of malignant diseases. Such cases were described in one generation, in distant relations of two and three generations and in monozygotic siblings. Either the same type of leukaemia was recorded or different types.

[Epidemiology and etiology of acute leukoses in children].

In their work authors have analyzed some epidemiologic and etiologic data that can be taken as the elements of risk in leukemogenesis. The investigations have been done retrospectively in 212 children suffering from acute leukemia and treated in Pediatric Clinic in Beograd. Certain factors of risk are particularly studied as: repeated viral infections, repeated use of antibiotics, diagnostic and therapeutic irradiation of children, familiar data on congenital anomalies and cancer and same harmful prezygotic and prenatal influences of possible significance.

[Calculosis of biliary and urinary tracts in children with congenital hemolytic anemias. (Retrospective view of some published work and certain investigations)].

During the last ten years twenty children with hereditary haemolitic anemia were admitted to the Children's University Hospital. As hyperbilirubinemia is one of the factors influencing calculi formation, we made systematic examination of the biliary and urinary pathways, because throughout these the excretory activity of bilirubin and its compound urobilinogen is performed. Owing to such a procedure, out of twenty children ten were discovered to have biliary calculi and other ten biliary and urinary calculi.