Excitation Transfer in Hybrid Nanostructures of Colloidal AgS/TGA Quantum Dots and Indocyanine Green J-Aggregates.

The regularities of the electron excitations exchange in hybrid associates of colloidal AgS quantum dots, passivated with thioglycolic acid (AgS/TGA QDs) with an average size of 2.2 and 3.7 nm with Indocyanine Green J-aggregates (ICG) were studied in this work by methods of absorption and luminescence spectroscopy.

Thioglycolic Acid FTIR Spectra on AgS Quantum Dots Interfaces.

The mechanism features of colloidal quantum dots (QDs) passivation with thioglycolic acid molecules (TGA) for cases of different luminescent properties is considered using FTIR. This problem is considered based on FTIR spectra analysis for various ionic forms of TGA. Experimental TGA molecules FTIR spectra is interpreted, basing on the data on modeling of TGA vibrational modes, realized in the framework of density functional method (DFT /B3LYP/6-31+G(d)) taking into account the vibrations anharmonicity of every functional group.

[Effects of water use conditions on cancer morbidity].

The study demonstrated that the cancer situation is tense in the Tsimlyansk area and it can be referred to a high malignant tumor morbidity and mortality zone. The sources of water supply of populated localities may be involved in the formation of malignant tumor morbidity rates.

[Epidemiologic characterization of Brucellosis under modern conditions].

The spread of brucella infection under modern conditions of cattle breeding were studied with the foci in the Rostov region taken as an example. The main epidemiological features and tendencies of epidemiological importance were established. To find out specific antigen in different environmental objects, the approbation of the enzyme immunoassay test systems was carried out and the possibility of their use at the institutions of the State Sanitary and Epidemiological inspection was shown.

The role of histamine H1-receptors in the modulation of neurotransmitter receptors activity in human lung cancer.

An abnormality in autonomic neural control in lung cancer has not yet been investigated. In the present work the role of histamine H1-receptors in the modulation of neurotransmitter receptors activity in human lung parenchyma in cancer is reported. It appeared that the activation of histamine H1-receptors may lead to the reduction of beta-adrenoceptors and the enhancement of muscarinic cholinergic receptors in cancer lung parenchyma.

[A case of the importation onto the territory of Russia of cholera caused by a new serovar].

Materials on the import of rarely occurring Vibrio cholerae, not belonging to group O1 of serovar O139, to the territory of Russia are presented. The clinical picture of a cholera case is described and the biological properties of V. cholerae, serovar O139, are presented.

[The complex study of the epidemic situation and of the immunological structure of the population in brucellosis foci].

As the result of the complex clinico-laboratory examination of 265 cattle breeders working on 5 farms where cases of brucellosis among agricultural animals had been detected, 62 persons (21.8%) were found to have the positive reaction to brucellosis. A strikingly high proportion (38.

The study of histamine H1- and H2-receptors in human lung cancer.

Data on human lung histamine H1- and H2-receptors in cancer and chronic inflammatory processes are reported. It has been found that the number of histamine H1-receptors significantly increases both in cancer and chronic pneumonia and does not practically change in tuberculosis lung parenchyma. The binding parameters of histamine H2-receptors both in cancer and inflammatory processes were similar to those obtained for the normal tissue.

Alterations in human lung adrenergic receptors in cancer.

Data on human lung alpha 1- and beta-adrenoceptors and the alpha 1/beta adrenergic ratio in cancer and chronic inflammatory processes are reported. The number of alpha 1-adrenergic sites markedly increased in lung cancer parenchyma, giving a ratio of alpha 1/beta binding sites of 12/1 in cancer but almost 1:1 in control specimens. The alpha 1/beta adrenergic ratio obtained both for mild and severe chronic pneumonia and tuberculosis lung parenchyma was similar to that demonstrated for normal tissue.

[The effect of antihistaminic preparations on the binding of labelled mepyramine, ketanserin and quinuclidinyl benzilate in the rat brain].

The effects of some antiallergic drugs on H1-histamine, 5-HT2-serotonin, and M-cholinoreceptors ligand binding in the rat brain were studied in vitro. Dimedrol, dimebon, and phencarol bonded to H1-receptors: IC50 were 76 +/- 10, 153 +/- 15, 320 +/- 60 nM, respectively. Diazoline and dimebon had some affinity for 5-HT2-receptors, its IC50 was 880 +/- 90 nM.

[Changes in human pulmonary receptors in tuberculosis, chronic pneumonia and cancer].

The authors studied changes in beta- and alpha 1-adrenoceptors (beta-AC, alpha 1-AC) as well as in m-cholinoceptors in tuberculosis, pneumonia and cancer. Specimens of the lung parenchyma were obtained at thoracic surgery from 43 patients. Relevant ligands binding to the receptors was evaluated by incubation of the membrane proteins with radioligands varying in concentrations.

[Alpha 1-adrenergic receptors in the liver parenchyma of children: the changes in cirrhosis].

In the present study alpha 1-adrenergic receptors have been investigated in liver parenchyma, obtained at the resection of prehepatic portal hypertension children without parenchymal affection (control group, n = 7) and the resection of children in parenchymal affection (group of cirrhosis, n = 8). It has been shown, that the binding of alpha 1-adrenergic antagonist 3H-prasozin (3H-PRZ) in liver parenchyma membranes of both control and cirrhosis groups is saturable and shows a high affinity. The Scatchard analysis of the binding data indicated that the binding site is characterized by Kd and Bmax of 0.

Human lung adrenergic and muscarinic cholinergic receptors in cancer and previous airways diseases.

In the present study adrenergic and muscarinic cholinergic receptors have been investigated in human lung parenchyma in cancer and previous airways diseases (chronic pneumonia, tuberculosis). It has been found that the number of muscarinic sites significantly increases in cancer and does not change both in chronic pneumonia and tuberculosis lung parenchyma in comparison with the normal tissue; the number of beta-adrenergic sites decreases in cancer, chronic pneumonia, as well as severe tuberculosis lung parenchyma. The important role of beta-adrenergic and muscarinic receptors in the formation of human lung adenocarcinoma is discussed.

[Adrenergic receptors in the liver parenchyma in children with chronic hepatitis].

In the present study adrenergic receptors have been investigated in liver parenchyma, obtained at the resection of extrahepatic portal hypertension children without parenchymal affection (control group, n-7) and the resection of children in parenchymal affection (group of chronic hepatitis children, n-6). It has been shown, that the binding of beta-adrenergic radioligand 3H-dihydroalprenolol (3H-DHA) in liver parenchyma membranes of both control and chronic hepatitis groups was saturable and showed high affinity. The Scatchard analysis of the binding data indicated that the binding site was characterized by Kd and Bmax of 1.

[Muscarinic acetylcholine receptors in peripheral human lung tissue: binding characteristics of 3H-quinuclidinyl-benzilate in malignancies].

Binding of muscarinic receptors antagonist 3H-quinuclidinyl benzylate (3H-QNB) was studied in human peripheral lung tissue, obtained after resection of pulmonary carcinoma and partial resection of tuberculoma from surrounding normal tissues (control group). Radioligand binding assays showed that binding of 3H-QNB in lung parenchyma membranes of both normal, healthy persons and patients with cancer was saturable with high rate of affinity. Saturation occurred at 1 nm concentration of the ligand.

[Alpha-adrenergic receptors of the human lung parenchyma in destructive tuberculosis].

Adrenergic receptors were studied in human lung parenchyma obtained from 10 patients with tuberculoma after segmental resection within the limits of surrounding normal tissues (controls) as well as from 10 patients with destructive pulmonary tuberculosis. Binding of alpha-adrenergic radioligand 3H-prazosin was saturable with high rate of affinity in lung parenchymal membranes of both normal tissues and tissues impaired with tuberculosis. The Scatchard analysis indicated that the affinity of 3H-prazosin binding was not altered in patients with tuberculosis, while amount of the ligand binding sites was significantly decreased as compared with control preparations (KD = 0.

[Chronic pneumonia and cancer: changes in beta-adrenergic receptors in human lung parenchyma].

beta-Adrenergic and muscarinic cholinergic receptors have been investigated in human lung parenchyma during cancer and chronic pneumonia as compared with normal tissue, obtained after segmental resection of tuberculoma from surrounding normal tissues. Binding of beta-adrenergic radioligand 3H-dihydroalprenolol (3H-DHA) and muscarinic antagonist 3H-quinuclidinyl benzylate (3H-QNB) was saturating with high rate of affinity in lung parenchyma membranes of both controls and patients with cancer and chronic pneumonia. Amount of binding sites of 3H-QNB was significantly increased in cancer (Bmax = 377.

[beta-Adrenergic and muscarinic acetylcholine receptors in human lung parenchyma in malignant neoplasms].

beta-Adrenergic and muscarine acetylcholinergic receptors were studied in human lung parenchyma obtained from patients with tuberculoma (after segmental resection of tuberculoma surrounding normal tissues were performed to obtain control samples) as well as from patients with pulmonary adenocarcinoma. Assays of binding of beta-adrenergic radioligand 3H-dihydroalprenolol (3H-DHA) exhibited high affinity in lung parenchyma membranes in both control samples and in that of patients with tumors. Binding of muscarine antagonist 3H-quinuclidinyl benzylate (3H-QNB) also showed high rate of affinity in lung parenchyma.

[The use of biochemical blood indices for the laboratory diagnosis of internal diseases using the automated complex device-computer].

Application of biochemical parameters of blood, reflecting disturbances in lipid, protein, carbohydrate, pigment and water-saline metabolism for diagnostics for internal organs diseases is discussed. Methods of clinical biochemistry in combination with subsequent automatic processing of the data obtained on the basis of probability theory and mathematical statistics methods can be used for preliminary computer diagnosis and further examination of a patient, as well as for construction of specific complexes of symptoms for some diseases. Due to their mobility, the preliminary computer diagnostics data can be successfully applied to different pathologies and groups of population.