Liver pathology in children with newly diagnosed celiac disease.

Aim Of The Study: To evaluate the prevalence and the type of liver pathology in children at the time of diagnosis of celiac disease (CD).

Material And Methods: Data from newly diagnosed children with CD hospitalized in the university hospital were retrospectively reviewed. Liver pathology was defined as elevated alanine transaminase (ALT) and/or gamma-glutamyl transpeptidase (GGT) serum activity and/or pathological changes of the organ in ultrasound.

A safe "cut, tie and thread-pull" method for percutaneous endoscopic gastrostomy tube removal in children with congenital craniofacial anomalies and pharyngeal stenosis.

Percutaneous endoscopic gastrostomy (PEG) is a widely used method for tube feeding with enteral nutrition. Both PEG's insertion and PEG's removal are usually easy and uncomplicated. The latter can be, however, of substantial difficulty in children with distorted anatomy, such as pharyngeal stenosis or endured craniofacial trauma, when regular endoscopy is contraindicated.

Mucosal gastrin cells and serum gastrin levels in children with Helicobacter pylori infection.

Purpose: Impaired control of gastric juice secretion is observed in chronic gastritis due to Helicobacter pylori (H. pylori) infection. G cells are stimulated by such cytokines as tumor necrosis factor (TNF-alpha), interferon gamma (IFN-gamma) and interleukin-8 (IL-8).

Soluble adhesion molecules ICAM-1, VCAM-1, P-selectin in children with Helicobacter pylori infection.

Aim: To assess the sICAM-1, sVCAM-1, and sP-selectin levels in children with Helicobacter pylori (H pylori) infection and to evaluate their significance for the morphological changes found in gastric mucosa.

Methods: The study included 106 children: 59 children (55.7%) with chronic gastritis and positive IgG against H pylori, 29 children (27.

[Clinical picture and morphological changes of upper intestinal tract mucosa in children with Helicobacter pylori infection].

The authors analysed clinical picture and morphological (macroscopic and histopathologic) changes in gastric and duodenal mucosa in 150 children diagnosed with Helicobacter pylori infection chosen randomly among the hospitalized in 1998-2000 years.

Macrophages of the antral mucosa in children with Helicobacter pylori infection and after eradication.

Our study included 59 children, aged 12.2 +/- 4.6 years, with Helicobacter pylori infection and 29 children, aged 11.

Memory cells in the antral mucosa of children with Helicobacter pylori infection.

A total of 106 patients, included in the study, were divided into three groups with regard to Helicobacter pylori infection. Endoscopy and histopathological examination of the stomach, based on the Sydney's System, were performed in all the children. CD45RA and CD45RO cells were identified by means of specific antibodies in the inflammatory infiltrate of the antral mucosa.

B (CD20+) lymphocytes in the antrum mucosa of children with Helicobacter pylori infection.

The aim of the study was to estimate the expression of CD20+ lymphocytes in the antrum mucosa in children, infected with Helicobacter pylori and after bacteria eradication. Biopsy specimens of gastric mucosa were the specimens, collected from 59 H. pylori-positive patients (Group I), 29 patients after H.

Helicobacter pylori infection and mast cells of the antrum mucosa.

The studies aimed at evaluating mast cells in inflammatory infiltration of gastric mucosa in children with H. pylori infection, as well as in those after the infection eradication. Biopsy specimens of gastric mucosa were evaluated, the specimens collected from 59 H.

Cytotoxic lymphocytes (CD8+) in the antrum mucosa in children with chronic Helicobacter pylori-related inflammation before and after bacteria eradication.

The authors assessed the expression of cytotoxic CD8 lymphocytes in the antrum mucosa of children with chronic Helicobacter pylori-related inflammation, before and after bacteria eradication. Biopsy specimens of gastric mucosa were evaluated in specimens, collected from 59 H. pylori-positive patients (Group I), 29 patients after H.

[Resistance to antibiotics used in Helicobacter pylori infection in children].

In literature and clinical findings, the attention has been turned to the resistance to the antibiotics used in Helicobacter pylori eradication, especially metronidazole and clarithromycin. Drug-resistance was evaluated in 50 children. Primary drug-resistance to the antibiotics used in eradications was determined in this group, and additionally, in 18 children who were subjected twice to unsuccessful eradicative therapy.

Comparative evaluation of gastric mucosa morphological changes in children and adults with positive IgG antibodies to Helicobacter pylori.

Purpose: Helicobacter pylori colonization of gastric epithelium causes a local and systemic, cellular and humoral immune response. Despite this immune response involvement in the infection, its elimination from the organism does not take place and the process usually becomes chronic. The purpose of the study was to establish the prevalence of gastric mucosa inflammation in children and adults with serum positive anti-Helicobacter pylori antibodies IgG.

Peripheral blood lymphocyte population in children infected with Helicobacter pylori.

Purpose: Helicobacter pylori infection in children is associated with a chronic inflammatory process of gastric and duodenal mucosa, which may have a various clinical course ranging from asymptomatic and chronic inflammatory condition to gastric ulceration. The immune system may contribute especially to chronic gastric mucosa inflammation. The aim of our study was to assess the levels of peripheral blood T (CD3+, CD4+, CD8+) and B lymphocyte subpopulation (CD19+) in children with Helicobacter pylori infection and to evaluate their relation to degree of antrum mucosa inflammation.

Lyme borreliosis--tick borne spirochaetosis among children.

The clinical picture of Lyme borreliosis in children in an early stage of the disease was presented. Treatment with Amoxicillin or Doxycycline led to the regression of clinical symptoms and elimination of specific antibodies within a three-month period of therapy in all cases.