Zh Nevrol Psikhiatr Im S S Korsakova
August 2024
The Foix-Alajouanine syndrome was originally reported by these authors in 1926, as rapidly progressive vasculitis on the background of a viral infection. The pathology was represented by the huge, more than 10 times, dilation either of the lumen, or the walls of the spinal vessels, either of the arteries, or the veins. There were no signs of thrombosis, no malformations.
View Article and Find Full Text PDFZh Vopr Neirokhir Im N N Burdenko
February 2024
Unlabelled: Femoral nerve damage, especially in proximal retroperitoneal space, is rare. Therefore, surgical strategy is still unclear for these patients. Various specialists discuss repair with autografts or neurotization by the obturator nerve or its muscular branch.
View Article and Find Full Text PDFZh Nevrol Psikhiatr Im S S Korsakova
November 2023
Motor neuron diseases (MND) include two main forms - amyotrophic lateral sclerosis (ALS) and spinal muscular atrophy (SMA). A certain part of these diseases is hereditary, while etiology of sporadic cases remains unknown. Both entities are known to develop because of motoneurons damage.
View Article and Find Full Text PDFOur aim was to determine parameters of motor evoked potential (MEP), elicited by the transcranial magnetic stimulation (TMS) from the tongue in healthy persons of different age. 62 neurologically healthy individuals without any speech problems (age range from 2 years old to 75 years, 34 females & 28 males) were enrolled. All underwent diagnostic TMS, single-pulse protocol, 90-sm round coil, Neiro-MS-D device.
View Article and Find Full Text PDFZh Nevrol Psikhiatr Im S S Korsakova
December 2014
Objective: To study the efficacy of the domestic recombinant interleukin-2 (IL-2) in the complex treatment of encephalitis.
Material And Methods: Forty patients, aged from 6 months to 17 years, were treated with the drug. A comparison group involved 35 patients who did not receive the drug.
Aim: To evaluate motor pathways involvement in children with multiple sclerosis.
Patients And Methods: We used transcranial magnetic stimulation method. 9 children with relapsing-remitting multiple sclerosis (mean duration 1,68 years) and 20 controls were enrolled.
The review considers the original and published data on the molecular genetic basis of proximal spinal muscular atrophy (SMA), the most common monogenic neuromuscular disease. The structures of the SMN1 gene and SMN2 pseudogene, mutations distorting the SMN1 function, the structure and functions of the Smn neurotrophic protein, its role in biogenesis of small nuclear ribonucleoproteins (snRNPs), and the principles and prdblems of molecular diagnosis in SMA are described. Special consideration is given to the current approaches and prospects of gene and cell therapy of SMA, pharmacogenetic methods to correct the SMN2 function, and original results of long-term treatment of SMA patients with valproic acid drugs.
View Article and Find Full Text PDFNeuromyalgic syndrome (NMS) is clinically and electroneuromyographically (ENMG) first-ever described in 50 children aged 2-13. Muscular pains and pains along peripheral nerves occur in post-infection period of acute respiratory viral infections (ARVI), intestinal and parotitoviral infections with transient (in 3-6 days), dysfunction of peripheral nervous system and muscles. NMS is characterized by predominant involvement of lower limb muscles in pathologic process and by rarely developing generalized form.
View Article and Find Full Text PDFZh Nevrol Psikhiatr Im S S Korsakova
December 2001
The paper presents clinical and neurological features of diphtheritic polyneuropathy in 110 patients aged from 6 months to 14 years. The pattern of neurological complications appeared to be quite different for nontoxic and toxic forms; electroneuromyographical criteria of preclinical diagnosis of nervous disorders were determined. The role of a vascular factor in demyelinating process' genesis, immunohomeostasis implications in severity and outcomes of diphtheritic polyneuropathies, prognostic factors of the unfavorable course of the disease were defined.
View Article and Find Full Text PDFNeurosci Behav Physiol
June 2000
Transdermal micropolarization of the spinal cord was performed in patients suffering sequelae of spinal cord trauma and tuberculous spondylitis. Changes in clinical and electrophysiological status were monitored. These studies demonstrated that the use of local direct currents passed via skin electrodes promoted improvements in motor and autonomic functions in these patients, leading to positive changes in measures of the functional state of the spinal cord and heart activity.
View Article and Find Full Text PDFZh Nevrol Psikhiatr Im S S Korsakova
January 1999
Transdermal micropolarization of the spinal cord was made in patients with consequences of the spinal cord injury or tuberculous spondylitis. Changes in clinical and electrophysiologic status were evaluated. It was found that local direct current through dermal electrodes promotes an improvement of both motor and autonomic functions in such patients.
View Article and Find Full Text PDFZh Nevrol Psikhiatr Im S S Korsakova
January 1996
The aim of the study was the investigation of central and peripheral pathogenetic mechanisms of torticollis spasmodic. It was examined 68 patients-37 with left pathology and 31-with right one. Electromyograms (EMG) were registered in m.
View Article and Find Full Text PDFZh Nevropatol Psikhiatr Im S S Korsakova
August 1989
Electromyography, electroneuromyography and monosynaptic N-reflex studies were performed in 61 patients with ischemic myelopathy. These data can be used to specify localization and the extent of the process. Its differentiation with several diseases providing a phenocopy of spinal disorders (tumors, lateral amyotrophic sclerosis syringomyelia, funicular myelosis) is discussed.
View Article and Find Full Text PDFFifteen patients with lateral amyotrophic sclerosis (LAS) and 37 patients with the LAS syndrome of vertebrogenic etiology were examined by global electromyography and recording of the H-reflex. The findings confirmed the diagnostic significance of electromyography in specifying the localization and severity of the pathological process. The method of monsynaptic testing was found to be especially valuable for diagnosing the disease at the early stage of development which helps to differentiate between LAS and the LAS syndrome of vertebrogenic etiology.
View Article and Find Full Text PDF