Publications by authors named "Komang Ardi Wahyuningsih"

Article Synopsis
  • The secretome of stem cells includes various bioactive factors that could be used as a treatment for skin aging, making it an appealing therapy option.
  • This systematic review evaluated the use of ascorbic acid (AA)-supplemented stem cell secretomes (SCS) for their potential in managing skin aging, analyzing studies from multiple databases.
  • Out of 1111 identified articles, only nine met the criteria for inclusion, indicating a need for more research to clarify the benefits of AA-supplemented SCS on skin health.
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Background: Ascorbic acid-2-phosphate has been reported to play a role in cell division and to suppress aging of cell. However, post-thawed cell morphology on various concentration of ascorbic acid is still unclear. In this study, we aimed to observe the morphology of post-thawed adipose-derived stem cells (ADSCs) in medium containing L-ascorbic acid-2-phosphate (LAA2P) (50 and 100 µg/mL).

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Background: Stromal vascular fraction (SVF) therapy has been performed over the past six years to treat 421 patients by our group in five clinical centers. Autologous SVF, which is a substance containing stem cells, was isolated from lipoaspirate, mixed with platelet-rich plasma (PRP), and administered to patients with degenerative diseases, autoimmune diseases, trauma, aging, and other diseases with unknown etiology. This study aimed to determine the safety of SVF and PRP that were given through infusion, spinal, and intra-articular injection.

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Background: Platelet-rich plasma (PRP) contains pro-angiogenic growth factors including vascular endothelial growth factor (VEGF). Angiogenesis is a necessary component of wound healing in instances of diabetic foot ulcers (DFU). PRP composition varies depending on methods and donor health status.

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