Population-based cohort across stroke life course in India-The NIMHANS-NH-SKAN stroke project: A study protocol.

Background: Stroke is a leading cause of death and disability worldwide. In India, it is the fourth leading cause of death and fifth leading cause of disability, posing a major public health concern. National surveys reveal an increasing trend in stroke risk factors such as tobacco use, physical activity, alcohol use, hypertension, and dyslipidemia.

Correction: Synthetic ramoplanin analogues are accessible by effective incorporation of arylglycines in solid-phase peptide synthesis.

[This corrects the article DOI: 10.1039/D3SC01944F.].

Multifunctional applications of bamboo crop beyond environmental management: an Indian prospective.

Increasing population, industrialization, and economic growth cause several adverse impacts on the existing environment and living being. Therefore, rising pollutants load and their mitigation strategies, as well as achieving energy requirements while reducing reliance on fossil fuels are the key areas, which needs significant consideration for sustainable environment. Since India has considerable biomass resources, bioenergy is a significant part of the country's energy policy.

Multicolour lanthanide(III) porous 1D coordination polymers: tunable wide spectrum emission and efficient Cu sensing.

Five isostructural 1D porous coordination polymers (PCPs) with a general formula of {[M(L)(DMF)(HO)]·1.5HO} [M = Tb (1), Eu (2), Yb (3), Nd (4) and Er (5)] have been synthesized using a flexible tripodal organic linker (L) and characterized. Tb (1) and Eu (2) PCPs exhibit metal-based green and red emission, respectively, whereas Yb (3), Nd (4) and Er (5) PCPs show near-infrared (NIR) emission.

Altered transcriptional regulatory proteins in glioblastoma and YBX1 as a potential regulator of tumor invasion.

We have studied differentially regulated nuclear proteome of the clinical tissue specimens of glioblastoma (GBM, WHO Grade IV) and lower grades of gliomas (Grade II and III) using high resolution mass spectrometry- based quantitative proteomics approach. The results showed altered expression of many regulatory proteins from the nucleus such as DNA binding proteins, transcription and post transcriptional processing factors and also included enrichment of nuclear proteins that are targets of granzyme signaling - an immune surveillance pathway. Protein - protein interaction network analysis using integrated proteomics and transcriptomics data of transcription factors and proteins for cell invasion process (drawn from another GBM dataset) revealed YBX1, a ubiquitous RNA and DNA-binding protein and a transcription factor, as a key interactor of major cell invasion-associated proteins from GBM.

Comparison of the influence of dental and facial aesthetics in determining overall attractiveness.

Objective: Orthodontic treatment aims at improving the perceived aesthetics; hence knowing which characteristics play a significant role in determining aesthetics is an important orthodontic objective. The aim of this study was to evaluate among laypersons, general dentists and orthodontists the importance of dental versus facial aesthetics.

Materials And Methods: Frontal face smile photographs of eight volunteers (4 males & 4 females), age group ranging from 16 to 24 years were used for the study.

Identification of a Novel Splice Variant of Neural Cell Adhesion Molecule in Glioblastoma Through Proteogenomics Analysis.

Splice variants are known to be important in the pathophysiology of tumors, including the brain cancers. We applied a proteogenomics pipeline to identify splice variants in glioblastoma (GBM, grade IV glioma), a highly malignant brain tumor, using in-house generated mass spectrometric proteomic data and public domain RNASeq dataset. Our analysis led to the identification of a novel exon that maps to the long isoform of Neural cell adhesion molecule 1 (NCAM1), expressed on the surface of glial cells and neurons, important for cell adhesion and cell signaling.

Excitation Energy Transfer Supported Amplified Charge-Transfer Emission in an Anthracenedicarboxylate- and Bipyridophenazine-Based Coordination Complex.

A highly luminescent tetrameric zinc(II) complex, {[Zn(adc)(bpz)(HCOO)]·2HO} (1; adc = 9,10-anthracenedicarboxylate and bpz = bipyridophenazine), was synthesized by a solvothermal technique and characterized by single-crystal X-ray diffraction. The linear tetrameric units extend into three dimensions via π stacking of adc/bpz and bpz/bpz and multiple CH-π interactions. The compound shows strong red emission at 597 nm (λ = 480 nm), which is attributed to charge-transfer (CT) emission within an adc/bpz donor-acceptor pair.