[The causes of late diagnostics of vestibular shwannomas].

Aim: The objective of the present study was to elucidate the causes of late diagnostics of vestibular shwannomas based on the results of the analysis of the medical histories of the patients admitted to the Academician N.N. Burdenko National Medical Research Centre of Neurosurgery for the management of this condition.

[The efficacy of botulinum therapy in treatment of delayed facial palsy after resection of vestibular schwannoma].

Unlabelled: Delayed facial palsy is a complication developing 3 or more days after surgery. The etiology and pathogenesis of this condition has not been fully explored, and there are no treatment standards for it. As in the case of Bell's paralysis, glucocorticosteroids (GCSs) are currently used to treat delayed facial palsy.

Microsurgical Treatment of Colloid Cysts of the Third Ventricle.

Background: This study analyzes the results of surgical treatment in 377 patients with colloid cysts (CCs) of the third ventricle who were treated at the Burdenko Neurosurgery Institute from 1981 to 2015. Operations were performed by a single surgeon (the first author of the article).

Methods: The transcallosal approach was used to remove CCs in 97% of cases.

[A clinical and neuropsychological study of patients before and after resection of third ventricle colloid cysts].

Unlabelled: The literature lacks studies of cognitive impairments in large groups of patients after resection of third ventricle colloid cysts.

Aim: To evaluate cognitive impairments in patients before and after resection of third ventricle colloid cysts.

Material And Methods: We performed a clinical and neuropsychological study of 52 patients with third ventricle colloid cysts using the Luria method (1962).

[Surgical treatment of trigeminal neuralgia in patients with multiple sclerosis].

Objective: Trigeminal neuralgia occurs in 1-7% patients with multiple sclerosis (MS). We assessed the efficacy of microvascular decompression of the trigeminal nerve in MS patients.

Material And Methods: We studied MS patients with trigeminal neuralgia who underwent microvascular decompression of the trigeminal nerve.

[Positional damage of the sciatic nerve during neurosurgical intervention into the posterior cranial fossa in the sitting position].

The paper describes a rare case of severe, but reversible bilateral damage to the sciatic nerve (compression neuropathy) in a patient with Blumenbach's clivus meningioma developing during 12-hour operation removing the tumor in the patient's sitting position on the operating table. The etiology and prevention of this complication are discussed.

[Endoscopic fenestration of median supratentorial cerebrospinal fluid cysts].

Mid-supratentorial liquor cysts are a relatively rare and generally congenital abnormality of the cerebral ventricles and subdural spaces. The data and views available in the literature on rational surgical policy is contradictory. The authors' experience in treating 16 patients was used to consider whether endoscopic techniques can be employed for invasive fenestration of the cysts.

[Clinical picture of colloid cysts of the III ventricle].

Clinical analysis of 74 cases of colloid cysts of the III-d ventricle was performed. Dynamics of clinical symptom complex was studied both in preoperative and early postoperative period as well as in remote periods after surgery. Most of the patients were treated in N.

Influence of phosphate ion on the fluorescence of 3-fluorotyrosine.

3-Fluorotyrosine fluorescence is quenched effectively by phosphate ions not only by a dynamic but also by a static mechanism owing to H-bond complex formation in ground state. 3-Fluorotyrosine pKa values both in the ground and first excited state (8.3 and 4, respectively) are appreciably lower than those of tyrosine, thus promoting 3-fluorotyrosinate ion formation in the excited state.

O-Perfluoroalkylation of 4-hydroxyphenylglycine.

Racemic N-Boc-4-difluoromethoxyphenylglycine was prepared by O-difluoromethylation of D-N-Boc-4-hydroxyphenylglycine under basic conditions, whereas the hexafluoropropylation reaction gives optically pure D-N-Boc-4-hexafluoropropoxyphenylglycine. D,L-4-difluoromethoxyphenylglycine was obtained by the action of TFA on the corresponding amino acid derivative.