[Mental disorders associated with acute COVID-19: clinical picture, therapy approaches].

Background: The purpose is to study the structure of clinical manifestations of mental disorders in the acute period of COVID-19 among patients, who were hospitalized with a new coronavirus infection and their relations with the severity of the immune response, to assess the efficacy and safety profile of the spectrum of used psychopharmacotherapy.

Material And Methods: A study was conducted of patients, hospitalized to the department of infectious diseases and repurposed for COVID-19 clinical departments with a diagnosis of COVID-19 (compliance with the criteria for ICD-10: U07.1) from September 2020 to March 2021.

Distinguishing Between Biological and Technical Replicates in Hypertension Research on Isolated Arteries.

Perivascular adipose tissue (PVAT) is implicated in the pathophysiology of cardiovascular disease, especially in obese individuals in which the quantity of renal and visceral PVAT is markedly increased. The control of arterial tone by PVAT has emerged as a relatively new field of experimental hypertension research. The discovery of this prototype of vasoregulation has been mostly inferred from data obtained using wire myography.

Ancient DNA reveals prehistoric gene-flow from siberia in the complex human population history of North East Europe.

North East Europe harbors a high diversity of cultures and languages, suggesting a complex genetic history. Archaeological, anthropological, and genetic research has revealed a series of influences from Western and Eastern Eurasia in the past. While genetic data from modern-day populations is commonly used to make inferences about their origins and past migrations, ancient DNA provides a powerful test of such hypotheses by giving a snapshot of the past genetic diversity.

[A survey of medical equipment displayed at the "Healthcare-2004" exhibition].

Surveyed in the paper is medical equipment displayed, November 29-December 3, 2004, in the Exhibition Hall in Krasnaya Presnya within the framework of the "Healthcare, Medical Equipment and Drugs-2004" Exhibition. The survey is made for the below categories of medical equipment: instruments and apparatuses; X-ray, neonatal, ophthalmologic and stomatological equipment; medical instruments; laboratory medical equipment; equipment for rehabilitation of patients and disabled and mobile medical equipment. A conclusion is made on that a lot of novel high-quality and high-tech medical equipment has emerged in the Russian market.

[The "Pulse" computer-based analyzer for measuring the pulse-wave and electric cardiac activity].

The paper deals with a device designed for the express-examination of the cardiac-vascular system through reading and processing the synchronously incoming electrocardiosignal and pulse-wave. The equipment is convenient for monitoring intraoperatively the functions of pacemaker due to its ability to select an optimal regimen not only for ECG but also for the pulse-wave. The new method of registering the pulse-wave by a miniature fiber-optic pressure sensor is described.

[History of development of manufacture of implanted pacemakers: plans and reality].

The paper deals with the history of design and development of implanted pacemakers, emphasis is also laid on electric neuromyostimulators. Present-day problems and prospects in this area are touched upon.

[Reduced paired stimulation in patients in the early postoperative period after an open-heart surgery].

The authors provide the technique of underdriving paired ventricular stimulation as a variant of treating drug-resistant tachycardias and a formula of calculating rhythm inhibition and the impulse delay. Basing on the stimulation pathophysiology and positive shifts in hemodynamics, the validity of this stimulation, its advantages and indications are inferred.

[The quality of life and survival of patients with an implanted pacemaker (the results of long-term observation)].

110 patients with implanted pacemaker were followed up for 1 to 10 years until a complete atrioventricular block. Permanent pacemaking is effective as it eliminates or reduces many symptoms, prolongs active life, improves quality of life in 81.4% of patients.

[Recommendations for implanting cardiac pacemakers in bradycardia].

The paper gives recommendations for cardiologists and cardiac surgeons who are engaged in working out indications, choice of the type and mode of cardiac pacing. Based on the understanding of the great importance of nomenclature documents concerning the development of indications for pacemakers implantation, the Working Group of the Expert Committee, Ministry of Health of the Russian Federation and Russian Academy of Medical Sciences, for implantable antiarrhythmic devices and electrophysiology has developed recommendations on pacemaker implantation in acquired atrioventricular (AV) block, in AV-block after myocardial infarction, chronic bi- and tri-fascicular block, sinoatrial nodal dysfunction, hypersensitive carotid sinus syndrome, neurovascular syndromes, as well as in childhood bradyarrhythmias. In developing the recommendations, the authors have used their own 25-year experience in implanting pacemakers and the recommendations proposed by the Working Group of the American College of Cardiologists and the American Association of Cardiologists in 1984 and 1991 for implanting pacemakers in bradyarrhythmias.

[Arrhythmia in patients after heart transplantation].

Holter monitoring was performed in 15 patients surviving over 3 months after homotopic cardiac transplantation. The frequency and types of arrhythmias occurring in the grafted innervated heart were studied according to its postoperative period duration. The follow-up lasted 3 to 29 months.

[The first clinical experience with heart transplantation].

The article analyses the first clinical experience in orthotopic allotransplantation of the heart at the Scientific Research Institute of Transplantology and Artificial Organs, USSR Ministry of Health, in the period from October, 1986 to July, 1989 (26 transplantations of the heart and one two-stage transplantation of the heart with the use of "Poisk-10M" artificial heart for 3.5 days in the first stage). Eleven patients are alive.

[Surgical treatment of different variants of tachycardia].

The paper presents a generalized experience in the surgical treatment of patients with frequent attacks of paroxysmal tachycardia associated with additional cardiac conduction pathways, that are not affected by the drug treatment. The results are described of 27 operations of destruction of anomalous cardiac conduction pathways. The use of a special ultrasound destructor permits the surgeon to perform the operation on the functioning heart, thus providing maximal radical surgery with minimal cardiac trauma and best effects.

[Coronary circulation in healthy men during postural changes and decompression of the lower half of the body].

The effect of postural changes (ortho- and antiorthostatic tests) and LBNP on coronary circulation was investigated in 11 healthy male test subjects. Volume blood flow velocity and pressure were measured and blood flowing from the heart was withdrawn using a Ganz catheter implanted into the coronary sinus. A thin Teflon catheter was implanted into the brachial artery.

[Topical diagnosis of disorders of the heart conduction system and surgical treatment of patients with supraventricular tachycardia].

Questions of preoperative diagnosis of the place of the disturbance of the normal heart excitation, spread of this excitation and distribution of places of the most frequent disposition of these foci in the heart depending on the pathology of the process are discussed. Sixty six patients with different kinds of tachicardia were examined, 40 patients were operated upon under conditions of artificial blood circulation. The examination of patients was performed by both routine and special methods (such as electrophysiological examination with the registration of 9 points of different parts of the heart simultaneously).