Pregnancy Rate after Controlled Ovarian Hyperstimulation and Intrauterine Insemination for the Treatment of Endometriosis following Surgery.

Objective: To compare pregnancy rate after controlled ovarian hyperstimulation and intrauterine insemination (COH-IUI) with no treatment in patients with endometriosis-associated infertility treated with laparoscopy.

Design: A clinical cohort study.

Setting: University-level tertiary care center.

BMI in relation to sperm count: an updated systematic review and collaborative meta-analysis.

BACKGROUND The global obesity epidemic has paralleled a decrease in semen quality. Yet, the association between obesity and sperm parameters remains controversial. The purpose of this report was to update the evidence on the association between BMI and sperm count through a systematic review with meta-analysis.

Effects of aromatase inhibitor on menopausal hyperplasia in a case of obesity.

The aromatase inhibitor anastrazole proved effective in the treatment of endometrial hyperplasia and postmenopausal bleeding in an obese 65-year-old woman with high operative risk. During anastrazole administration for 12 months, the endometrial thickness decreased from 9.8 mm to 2.

A boy or a girl? A Hungarian survey regarding gender selection.

Background: Infertile Hungarian couples were surveyed with regard to their opinion of preconception gender selection by the separation of X- and Y-bearing sperm populations.

Methods: Self-completion of a questionnaire. Group 1: subjects presenting for infertility examination; Group 2: presenting for homologous intrauterine insemination.

Effect of body weight on testosterone/estradiol ratio in oligozoospermic patients.

To evaluate the effect of body mass on the hormonal and semen profiles of subfertile men with oligozoospemia, sperm concentration and reproductive hormone levels were compared in two body mass index (BMI) groups: underweight or normal weight patients (BMI = 25 kg/m2) vs. overweight or obese patients (BMI > 25 kg/m2). The mean BMI was 27 +/- 4.

Is semen quality affected by male body fat distribution?

The aim of this study was to examine the relationship of semen parameters, sexual function-related hormones and waist/hip ratio. Eighty-one selected patients presenting with infertility were examined. Weight, height, waist circumference and hip circumference were measured, and reproduction-related hormone levels were determined.

Is there a relationship between cell phone use and semen quality?

This study was conducted to determine a possible relationship between regular cell phone use and different human semen attributes. The history-taking of men in our university clinic was supplemented with questions concerning cell phone use habits, including possession, daily standby position and daily transmission times. Semen analyses were performed by conventional methods.

Effect of body weight on sperm concentration in normozoospermic males.

A total of 274 men (aged: 26 +/- 4.9 years) with normozoospermia were enrolled into this study. Their body mass index (BMI: kg/m2) varied between 17 and 39.

Low-dose ovulation induction with urinary gonadotropins or recombinant follicle stimulating hormone in patients with polycystic ovary syndrome.

Patients with polycystic ovary syndrome (PCOS) are highly sensitive to gonadotropins. In recent years a number of publications have shown that chronic low-dose protocols are effective in reducing complications, in particular ovarian hyperstimulation syndrome (OHSS), especially if recombinant human follicle stimulating hormone (rhFSH) is used. The aim of the present study was to compare the efficacy and safety of rhFSH (Gonal-F, Serono) versus urinary human FSH (uhFSH) (Metrodin, Serono) in a low-dose step-up protocol for ovulation induction in clomiphene-resistent infertile PCOS patients.

Magnesium-orotate supplementation for idiopathic infertile male patients: a randomized, placebo-controlled clinical pilot study.

A randomized, placebo-controlled clinical pilot study was performed in order to examine the effect of magnesium-orotate in male idiopathic infertility. Ten males were treated daily for 90 consecutive days with 3000 mg magnesium-orotate (Magnerot) tablets (Group M). As a control, ten other males were treated in the same way with placebo (Group P).

Effect of female body weight on efficiency of donor AI.

A total of 1,144 infertile women were treated by artificial donor insemination. Unsuccessful ovulation induction was found in 96 of these cases. The obese women (BMI: 28-36) had a relative risk of unsuccessful ovulation induction of 2.

Results of insemination (AIH) following GnRH treatment of endometriosis.

Endometriosis is one of the most frequent benign diseases in gynecology. It is the cause of the pelvic pain and infertility in more than 35% of women of reproductive age. The most appropriate treatment for endometriosis is the combination of surgery and adjuvant medical therapy with GnRH agonists.

[Treatment of hyperprolactinemic anovulation with the dopamin-agonist quinagolide].

Quinagolide has a strong dopaminerg activity, suppresses prolactin secretion and restores gonadal function in women with hyperprolactinemic anovulation. The aim of our study was to investigate the effectiveness of quinagolide in the treatment of 16 hyperprolactinemic patients. The clinical diagnosis was functional hyperprolactinemia in 13 patients, microprolactinoma in 2 and empty sella syndrome in 1.

[The value of plasma prolactin level determination in the diagnosis of postmenopausal osteoporosis].

Anovulation condition (estrogen deficiency due to high prolactin level) is linked with premature loss of bone mass. Bone mineral density was measured in the femur neck and the lumbar spine (L2-L4) with DEXA and the bone density was given by Z-score, which makes comparison to adult women's bone mass (normal reference). The examinations were carried out in two different groups.

[Ovulation induction with adjuvant antiandrogen treatment in Stein-Leventhal syndrome].

Ovulation induction with adjuvant antiandrogen treatment was carried out in 50 cycles of 24 hyperandrogenic anovulatory patients. Besides the clomiphene and gonadotrophin (pure FSH) administration on the bases of antiandrogenic effects of the drugs three treatment groups (dexamethasone, sprinolactone and cyproterone acetate) were established. In 40 cases of 50 cycles ovulation were detected and 11 pregnancies occurred.

[Treatment of climacteric urogenital disorders with an estriol-containing ointment].

Estriol containing cream for treatment of climacteric urogenital complaints was used. After 4 weeks local treatment with Ovestin cream atrophy of vaginal epithelium and chronic vaginitis stopped or significantly decreased. During the treatment the ratio of superficial and intermedier cells in the vaginal epithelium increased and the vagina showed a decrease of pH.

[Pulsatile gonadotropin releasing hormone treatment following previous ovarian hyperstimulation].

Physiological follicular maturation was achieved by pulsatile gonadotrophin releasing hormone treatment in ovarian hyperstimulatory cases induced previously by other ovulation induction methods (clomiphene, clomiphene + hCG, clomiphene + hMG + hCG). The follicular development was detected by vaginal ultrasound examination (Hitachi-3000, 6.5 MHz) in 8 cycles treated with gonadotrophin releasing hormone.

[Changes in melatonin blood levels during gonadotropin releasing hormone loading tests in women with anovulatory disorders].

The results of seven gonadotropin releasing hormone (GnRH) loading tests are presented with special respect to the changes of melatonin level. The tests were carried out after a withdrawal bleeding triggered by progesterone (100 mg for 5 days) and plasma FSH, LH, prolactin and melatonin level were determined. The initial melatonin values were between 3.

[Gonadotropin releasing hormone loading test with bromocryptin therapy: a new possibility in the differential diagnosis of normo-prolactinaemic anovulation].

An anovulation group with normal basal prolactin level (less than 600 mU/l) was found during GnRH loading tests. After GnRH administration there was a definite increase in prolactin value together with an insufficient hypophyseal response. Bromocriptine treatment was commenced on the 10th day (daily 2.

[Pulsatile gonadotropin-releasing hormone substitution following excision of a craniopharyngioma with suprasellar invasion].

Craniopharyngeoma growing suprasellary attacks the medio-basal region of hypothalamus, that leads to the stopping of the production of gonadotropin releasing hormone. In connection with the case of a 15-year-old girl who had partial extirpation of craniopharyngeoma the authors write about the favourable endocrine effect of pulsatile gonadotropin releasing hormone treatment. Through giving gonadotropin releasing hormone every 90 minutes in 20 micrograms doses menstruation cycle and ovulation was performed.

Pulsatile gonadotropin releasing hormone substitution following extirpation of suprasellar craniopharyngioma.

A craniopharyngioma growing suprasellarly attacks the medio-basal region of the hypothalamus, interrupting the production of gonadotropin-releasing hormone. In the case of a 15-year-old girl who underwent partial extirpation of craniopharyngioma, favorable endocrine effects were obtained by pulsatile gonadotropin-releasing hormone treatment. Gonadotropin-releasing hormone administered in a dose of 20 micrograms every 90 min resulted in the achievement of a menstrual cycle and ovulation.

[Treatment of functional infertility, caused by luteal deficiency, with pulsatile perfusion of gonadotropin releasing hormone].

The prehistory of cyclical development of corpus luteum goes back to early follicular phase. Reduced secretion or defective rhythm of gonadotropin releasing hormone (GnRH) can later cause unperfect ovulation or corpus luteum insufficiency. The authors carried out a low-dose pulsatory GnRH-treatment on eight patients with luteal insufficiency, who were earlier treated unsuccessfully with other ovulation-inductive methods (clomiphene, hCG, bromocryptin).

[Changes in the prolactin level under the effect of pulsatile infusion of gonadotropin releasing hormone].

Plasma prolactin levels were measured in 18 GnRH loading tests and, in 24 cycles involving treatment with GnRH. During 17 GnRH loading tests the prolactin levels production remained virtually unchanged, the individual GnRH pulses not raising the prolactin level. In one case the GnRH loading test led to a considerable rise in prolactin level, which is considered to be a pathological prognostic sign as concerns subsequent GnRH treatment.