[Role of lipid peroxidation in the regulation of liver microsomal monooxygenase activity in homoiothermic animals exposed to cold].

The reaction rates of N-demethylation of aminopyrine, p-hydroxylation of aniline and hydroxylation of 3,4-benzo(a)pyrene in liver microsomes were determined in rats exposed to severe cold (-7 degrees C) for a long time (8 days). The data obtained demonstrate the decreased activities of 3,4-benzo(a)pyrene hydroxylase and aniline hydroxylase. There were no distinct alterations in aminopyrine N-demethylase activity.

[Various aspects of blood platelet function of patients who have sustained an ischemic stroke or myocardial infarct and of their relatives].

The authors examined the functional properties of platelets (adhesion, serotonin content and its absorption by the cells) in patients with atherosclerosis who had suffered an ischemic stroke or myocardial infarction, as well as in their relatives and in healthy subjects (control). All the patients were comparable as to the age. In the atherosclerotic patients distinct disturbances of the platelet functional properties were revealed.

[Lipid peroxidation response in the liver and lungs of rats during prolonged cold adaptation].

Prolonged cold adaptation in rats (+4-6 degrees C) is associated with phasic changes in lipid peroxidation. On the 7th day the quantity of liquid peroxidation products in the liver and lungs and the ability of liver lipids to take part in the ascorbate-dependent peroxidation were increased. Meanwhile the antioxidant activity of lipids was decreased.

[Effect of heparin on the lipid peroxidation reaction of erythrocytes and their stability].

Physiological concentration (10 units/ml) of heparin activates ascorbate-dependent lipid peroxidation of erythrocytes and reduces their stability in the citrate-phosphate buffer (pH 3.0). In a concentration of 100 units/ml heparin does not influence the thermal (62 degrees) oxidation of methyloleate.