Publications by authors named "Kolle Johanna"

Objective: The aim of the present study was to objectively assess the degree of residual facial asymmetry after primary treatment of non-syndromic unilateral cleft lip and palate (UCLP) in children and to correlate it with subjective ratings of facial appearance.

Materials And Methods: Stereophotometry was used to record the faces of 89 children with UCLP for comparison of cleft and non-cleft sides up to 5 years after primary cleft closure. Root mean square values were calculated to measure the difference between the shape of cleft and non-cleft sides of the face and were compared to controls without a cleft lip.

View Article and Find Full Text PDF
Article Synopsis
  • The study aimed to evaluate the necessity of secondary palatal corrective surgery in a specific repair protocol for cleft palates, focusing on a phased approach to palate closure.
  • Data was analyzed from 195 patients treated at the University Goettingen between 2001 and 2021, looking at surgery types, complications like oronasal fistulae, and incidences of secondary surgeries.
  • Results indicated that only 1% of the patients required additional palatal surgeries, and about 19% of older patients needed skeletal corrective surgeries, suggesting the protocol was effective in minimizing complications.
View Article and Find Full Text PDF
Article Synopsis
  • The study aimed to gather clinical and epidemiological data on patients with orofacial clefts in Lower Saxony, analyzing records from 404 surgical cases at the University Medical Center Goettingen from 2001 to 2019.
  • The prevalence of orofacial clefts was found to be 1:890, with cleft lip and palate (CLP) being the most common type, and almost 10% of patients had syndromic conditions; factors like family history and pregnancy complications were also examined.
  • The findings highlighted the need for specialized care, as the profiles of syndromic CL/P and associated health issues were significant, aligning with trends seen in other Western populations.
View Article and Find Full Text PDF

Background: Renal injury is a serious complication after cardiac surgery and therefore, early detection and much more prediction of postoperative kidney injury is desirable. Neutrophil gelatinase-associated lipocalin (NGAL) is a predictive biomarker of acute kidney injury and may increase after cardiopulmonary bypass (CPB). However, time correlation of NGAL expression and severity of renal injury is still unclear.

View Article and Find Full Text PDF