HLA alleles and susceptibility to dermatological disorders associated with Helicobacter pylori infection: a significant association to HLA-Cw*06.

The occurrence rate of HLA class I and class II alleles was established in 24 patients suffering from dermatological disorders associated with the Helicobacter pylori infection. The increased frequency of HLA-C*0602, 4 was found to be 0.1875 compared to 0.

Occurrence rates of HLA-DRB1, HLA-DQB1, and HLA-DPB1 alleles in patients suffering from vitiligo.

By investigating a group of 39 unrelated adults suffering from vitiligo it was found that alleles HLA-DRB1*0701, -DQB1*0201, and -DPB1*1601 differed in their frequencies in comparison to those observed in the healthy population. The allele HLA-DRB1*0701 was found in 26.5% of patients compared to 14.

[An unusual "black-dot" trichophytosis corporis in a man].

The authors describe an infectious disease, rarely occurring in the Slovak Republic-superficial trichophytia caused by Trichophyton tonsurans var. sulphureum-in a 37-year-old male patient with psoriasis. Untreated oval to circular foci 4-10 x 5-12 cm in size were localised on the forearms and knee, gradually developing black dots remaining after broken hair (parasitismus endothrix).

[Atypical infection caused by Microsporum gypseum mimicking circumscribed scleroderma].

The authors describe a case of a 31 year old woman who suffered from sclerodermia circumscripta on her right leg. The diagnosis was histopathologically verified. Capillaroscopy and respiratory obstruction were positive.

Vitiligo is associated with HLA-A2 and HLA-Dw7 in the Slovak populations.

By investigating a group of 67 unrelated adult persons suffering from vitiligo it was found that antigens HLA-A2 and HLA-Dw7 differed in their frequencies in comparison to those observed in the healthy population. The antigen HLA-A2 was found in 76.12% of patients compared to 43.

[Vitiligo--an enigmatic disease. II. Therapy of vitiligo].

The work gives a review of therapeutic methods of vitiligo. PUVA therapy, application of cortisonoids, khellin (including UVA), phenylalanine (including UVA), melagenina, and laser therapy represent non-surgical methods. Surgical methods include application of fluorouracil following dermabrasion, of autologous epidermal grafting transplantation of in vitro cultured epidermis, in vitro cultured melanocytes and micropigmentation by pigment.