[A comparative study of the antioxidant properties of polyhydroxamic acids, desferal and other iron chelating agents].

The effects of different iron chelators on both OH.-generation in Fenton reaction and lipid peroxidation products accumulation in brain homogenate were studied. Intensity of luminol-dependent chemiluminescence was the measure of OH.

[Synthesis and analysis of glycol bis-phosphates, regulators of reversible hemoglobin oxygenation].

Bisphosphates of glycols, ethyleneglycol and 1,2-propanediol, were synthesized. These structural analogues of 2,3-diphosphoglyceric acid were shown to reduce significantly the oxygen affinity of stripped hemoglobin.

[Synthesis and properties of an organophosphorous regulator of hemoglobin oxygenation].

Racemic 1-O-(epsilon-aminohexanoyl)-2,3-diphosphoglycerol (ADPG) was synthesized. The pH dependence of the 31P-NMR spectra was studied for the ADPG cyclohexylammonium salt. ADPG binding to hemoglobin and its functional activity as a regulator of human hemoglobin reversible oxygenation were assayed.