Publications by authors named "Koki Okamoto"
Commun Biol
February 2023
Article Synopsis
- Triple-negative breast cancer (TNBC) is a challenging and aggressive form of cancer with limited treatment options and higher mortality rates compared to other breast cancer types.
- Research indicates that mammary gland tissue-resident macrophages (MGTRMs) are the most common cells present in early TNBC and contribute to tumor growth and progression.
- Depleting MGTRMs before TNBC cell transplantation significantly hinders tumor growth and improves outcomes in terms of tumor recurrence, metastasis, and chemotherapy effectiveness, suggesting a new potential target for TNBC treatment.
