Publications by authors named "Koki Norikawa"
Article Synopsis
- The study aimed to understand the relationship between arm-to-choroidal circulation time (ACT) and clinical outcomes in patients with polypoidal choroidal vasculopathy (PCV) using indocyanine green angiography.
- Researchers analyzed 38 patients' eyes, dividing them based on ACT duration (≥20 s vs. <20 s) and found significant differences in retinal fluid accumulation and hemorrhage recurrence between the two groups.
- The findings suggest that patients with longer ACT (>20 s) are at a higher risk of experiencing complications during treatment, as they have more polypoidal lesions.
Purpose: To assess the changes in intraocular pressure (IOP) after intravitreal aflibercept injections in Japanese patients with neovascular age-related macular degeneration (nAMD) complicated by glaucoma.
Study Design: Retrospective observational study.
Methods: We retrospectively reviewed 27 eyes of 25 Japanese patients diagnosed with nAMD complicated by glaucoma.
Sixty-seven patients (38 woman; median age, 69 years) were enrolled to assess complement activation products (CAPs) in tear fluid with/without dry eye (DE) and with/without meibomian gland dysfunction (MGD). Patients were divided into four groups based on the presence/absence of DE and MGD: group DM had both DE and MGD, group DN had DE without MGD, group NM had MGD without DE, and group NN had neither DE nor MGD. The levels of C3a and C5a in the collected tears were analyzed using a cytometric bead array.
View Article and Find Full Text PDFPurpose: Due to technological advancements, surgical invasiveness has been reduced. However, cataract surgery has been implicated in causing postoperative inflammation, including dry eye syndrome. The innate immune system may be involved in postoperative inflammation, and complement activation could potentially play a crucial role in defense against pathogens, homeostasis, and wound healing.
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