Publications by authors named "Koki Matsuoka"
Background: Repeat endoscopic submucosal dissection for metachronous recurrence of esophageal squamous cell carcinoma close to previous endoscopic submucosal dissection scars is challenging. Therefore, this study evaluated the efficacy and safety of repeat endoscopic submucosal dissection for recurrent esophageal squamous cell carcinoma.
Methods: The study included 1680 patients.
Article Synopsis
- This study investigates risk factors and post-ESD management strategies for pyloric stenosis after endoscopic submucosal dissection (ESD).
- Researchers analyzed 159 pyloric ESD cases, identifying patients with circumferential mucosal defects ≥ 76% as high-risk for stenosis.
- They found that stenosis typically develops between weeks three to eight after the procedure, but most cases can be effectively treated with endoscopic balloon dilation without complications.
Cytotoxin-associated gene A (CagA) is generally accepted to be the most important virulence factor of Helicobacter pylori and increases the risk of developing gastric cancer. East Asian CagA, which includes the EPIYA-D segment at the C-terminal region, has a significantly higher gastric carcinogenic rate than Western CagA including the EPIYA-C segment. Although the amino acid polymorphism surrounding the EPIYA motif in the C-terminal region has been examined in detail, limited information is currently available on the amino acid polymorphism of the N-terminal region of East Asian CagA.
View Article and Find Full Text PDFEffects of Helicobacter pylori on the glutathione-related pathway in gastric epithelial cells.
Biochem Biophys Res Commun
June 2020
Virulence factors of Helicobacter pylori (H. pylori) are diverse, so various biological responses happen in a host infected with H. pylori.
View Article and Find Full Text PDFArticle Synopsis
- The study investigates edge artifacts in PET images using point spread function correction for gallium (Ga) and fluorine (F) isotopes, noting that Ga has a longer positron range than F.
- Using a specific body phantom filled with Ga and F solutions, PET data were collected and analyzed for artifacts and radioactivity profiles.
- Results indicated that Ga-PET had less prominent edge artifacts and lower overshoot levels compared to F-PET, suggesting that the differences in positron range contribute to these discrepancies in image quality.
Article Synopsis
- - This study investigates how the shape and size of regions-of-interest (ROIs) and volumes of interest (VOIs) affect the signal-to-noise ratio (SNR) in liver imaging using F-FDG PET scans for cancer screening.
- - It analyzed data from 108 patients, comparing results from different diameter ROIs and VOIs on the liver, finding that while SUV measurements were consistent, the SNR varied significantly between different types.
- - The findings suggest that using a 4-cm-diameter spherical VOI yields the most stable and reproducible SNR, emphasizing the importance of ROI and VOI selection in imaging quality assessments.