Influence of Warning Bleeding on Blood Loss in Low-Lying Placenta.

Objective This study aimed to investigate whether the amount of blood loss during delivery in patients with low-lying placenta is affected by the planned mode of delivery, internal os distance, and warning bleeding. Materials and methods We conducted a single-center retrospective study encompassing women with singleton pregnancies diagnosed with low-lying placenta between January 2012 and December 2021. Data for maternal demographic details and pregnancy outcomes were extracted from the institution's records.

Comparison of open and laparoscopic appendectomy according to the trimester of pregnancy: A nationwide observational study.

Objective: To compare the outcomes of open appendectomy (OA) and laparoscopic appendectomy (LA) for acute appendicitis during pregnancy by trimester.

Methods: We conducted a nationwide retrospective cohort study using the Diagnosis Procedure Combination database in Japan. We identified pregnant women diagnosed with appendicitis who underwent OA or LA from 2010 to 2022.

Resonance-enhanced multiphoton ionization time-of-flight mass spectrometry for direct analysis of liposome-encapsulated compounds.

The direct measurement of compounds encapsulated into liposomes without pretreatment allows verification of both the encapsulation efficiency and the release rate of liposomes in their original state. In the present study, the direct analysis of liposomes was conducted via resonance-enhanced multiphoton ionization time-of-flight mass spectrometry (REMPI-TOFMS). When analyte species (2-phenoxyethanol) encapsulated in liposomes were measured online, spike signals appeared in a time profile of the peak area for 2-phenoxyethanol, which suggested a dispersion of the compound in this sample.

Pregnancy Following Spontaneous Healing of Uterine Rupture: A Case Report and Experience of Management.

Uterine rupture can heal naturally without the need for surgical intervention. However, reports on subsequent pregnancies are limited. A 27-year-old woman, gravida 2, para 1, visited our institution at seven weeks of gestation.

Impact of gestational age on the management of acute appendicitis during pregnancy: A nationwide observational study.

Objective: To compare conservative management and appendectomy for acute appendicitis during pregnancy by trimester.

Methods: This retrospective cohort study used data from a national inpatient database from July 2010 to March 2022. Pregnant women diagnosed with acute appendicitis were included.

In-hospital outcomes of repair and hysterectomy for uterine rupture: A nationwide observational study.

Objective: Uterine rupture, though rare, poses significant risks to both mother and child. Its occurrence varies globally, with a noted 0.015% prevalence in Japan.

Updated criteria for the approval of subsequent pregnancy after cesarean section with a transverse uterine fundal incision based on 17 years of experience.

In the case of placenta previa-accreta when the placenta covers the entire anterior uterine wall, it is difficult to avoid transecting the placenta by traditional low-transverse cesarean section (CS), resulting in catastrophic hemorrhage and fetal anemia. To prevent this critical risk, we developed the CS with transverse uterine fundal incision (TUFI) and this technique has been widely used as a beneficial surgical method in clinical practice owing to its safety advantages for the mother and neonate since our first report. However, the risk of uterine rupture during a subsequent pregnancy remains unclear.

Evaluation of incision healing status after transverse uterine fundal incision for cesarean delivery and postoperative pregnancy: a ten-year single-center retrospective study.

Background: Transverse uterine fundal incision (TUFI) is a beneficial procedure for mothers and babies at risk due to placenta previa-accreta, and has been implemented worldwide. However, the risk of uterine rupture during a subsequent pregnancy remains unclear. We therefore evaluated the TUFI wound scar to determine the approval criteria for pregnancy after this surgery.

The three-factor structure of the Autism-Spectrum Quotient Japanese version in pregnant women.

Background: There is a rising interest in perinatal mental health studies, and proper psychometric tools to assess autistic traits among this population in Japan are vital.

Objective: This study aimed to clarify the optimal factor structure of the AQ as part of a perinatal mental health research project.

Methods: We used the Japanese version of the AQ (AQ-J) to measure autistic-like traits in pregnant women.

Dedifferentiated fat cells administration ameliorates abnormal expressions of fatty acids metabolism-related protein expressions and intestinal tissue damage in experimental necrotizing enterocolitis.

Neonatal necrotizing enterocolitis (NEC) is a serious disease of premature infants that necessitates intensive care and frequently results in life-threatening complications and high mortality. Dedifferentiated fat cells (DFATs) are mesenchymal stem cell-like cells derived from mature adipocytes. DFATs were intraperitoneally administrated to a rat NEC model, and the treatment effect and its mechanism were evaluated.

Obstetrical outcomes of pregnant women 50 years and older compared to those aged 45-49 years: A systematic review and meta-analysis.

Aim: In this review, We compared clinical characteristics of pregnant women aged 50 and older with those aged 45-49. Pregnant women ≥45 years are strongly associated with pregnancy-related complications, such as cesarean section rate, gestational hypertension, gestational diabetes mellitus, and preterm birth. Although pregnant women ≥50 years are considered more high-risk, differences in pregnancy outcomes between those over 45 and 50 years of age are unclear.

Pregnancy outcomes at maternal age over 45 years: a systematic review and meta-analysis.

Objective: This study aimed to identify trends in pregnancy outcomes, especially delivery mode, among pregnant patients older than 45 years.

Data Sources: A literature search was performed using PubMed, Web of Science, and the Cochrane Central Register of Controlled Trials for studies published between January 1, 2010, and June 30, 2022.

Study Eligibility Criteria: The primary outcomes were cesarean delivery and assisted delivery.

Unexpected uterine body placenta accreta spectrum with placenta previa in a subsequent pregnancy after uterine artery embolization: a case report.

Background: A subsequent pregnancy after uterine artery embolization (UAE) raises several concerns, one of which is placenta accreta spectrum (PAS). Placenta previa is the strongest risk factor for PAS, which is most likely to occur in the lower uterine segment. PAS without placenta previa (i.