Treatment Selection and Characteristics of Patients With Preiser Disease.

Purpose: Preiser disease is difficult to diagnose and treat because of its unclear pathophysiology. Although both nonsurgical treatment and surgical treatment for Preiser disease have been reported, there is no consensus on the optimal treatment because of its rarity. The purpose of this study was to investigate the relationship between treatment selection and characteristics of patients with Preiser disease.

Biomechanical Analysis of a New Odd-Numbered Strand Suture Technique for Early Active Mobilization After Primary Flexor Tendon Repair.

Purpose: The placement of multistrand sutures during flexor tendon repair is complex and challenging. We developed a new, simpler, nine-strand suture, which we term the Tajima nines. The Tajima nines repair method is a new odd-numbered strand tendon technique.

A Simple Technique Ensuring Adequate Exposure During Primary Repair of Complex Thumb Injuries.

As the thumb is pronated, primary repair of complex injuries may be more difficult than the repair of other digits. We describe a simple technique that facilitates thumb repair. We insert a Kirschner wire perpendicular to the bone axis in the middle of the proximal phalanx, which ensures adequate exposure of the palmar aspect without the need for thumb position adjustment by an assistant.

Long-term Follow-up of Hand-degloving Injury Treated by Conventional Methods.

Despite medical advances, degloving injury remains one of the most difficult traumatic injuries to treat. The conventional method for treating degloving injury of the hand is reconstruction with a groin flap. However, few reports have described the mid- or long-term functional and aesthetic outcomes after a hand reconstruction with a groin flap.

The Duration of Bone Healing and Nonunion Ratio After Ulnar Shortening Osteotomy Using a 5-Hole Forearm Compression Plate With Transverse Osteotomy.

Background: Ulnar shortening osteotomy using various osteotomy sites, osteotomy methods, and surgical techniques with a variety of implants has been reported, but nonunion rates and the duration of bone healing are not uniform by the authors. The purpose of this study was to investigate the duration of bone healing and nonunion ratio in patients who underwent ulnar shortening osteotomy by a 5-hole nonlocking plate with a simple transverse osteotomy for ulnar impaction syndrome and to determine the correlation between the gap length of the osteotomy site and the duration of bone healing.

Methods: We assessed patients who underwent ulnar shortening osteotomy for ulnar impaction syndrome using a 5-hole nonlocking plate fixation followed by a simple transverse osteotomy between July 2012 and October 2021.

Forty-Two-Year Follow-Up After Heterodigital Vascularized Hemijoint Transfer: A Case Report.

Heterodigital vascularized hemijoint transfer can theoretically produce a near normal joint by combining intact joint components from different fingers and maintaining the joint space over the long term. We present herein an extremely rare case of heterodigital vascularized hemijoint transfer with a 42-year follow-up, demonstrating the longevity of this joint reconstruction technique for the restoration of hand function. Our patient's outcome indicates that despite the gradual progression of osteoarthritic changes, good subjective results and maintenance of an active range of motion can be acquired even after a long period.

A Novel Reconstruction Technique for Chronic Distal Biceps Tendon Rupture: A Case Report.

Case: A 71-year-old otherwise healthy man presented with an 8-week history of elbow pain and weakness in both elbow flexion and forearm supination. Magnetic resonance imaging revealed complete rupture of the distal biceps tendon insertion associated with 65 mm of proximal retraction. At 10 weeks after initial injury, the patient underwent a novel reconstruction technique using a periosteal flap from the iliac crest; subsequently, all symptoms resolved.

Japanese version of the Patient-rated elbow evaluation score correlates with physician-rated Japanese orthopaedic association-Japan elbow society elbow function score.

Background: The association between Patient-Rated Elbow Evaluation: Japanese version (PREE-J) and Japanese Orthopaedic Association-Japan Elbow Society Elbow Function score (JOA-JES score) is unclear. This study evaluated the association between PREE-J and JOA-JES scores.

Methods: The patients with elbow disorders were divided into two groups: Group A (conservative treatment, n = 97) and Group B (surgical treatment, n = 156).

Biomechanical Analysis of a New Eight-Strand Suture for Flexor Tendon Repair.

 The placement of multistrand sutures during flexor tendon repair requires complicated surgical skills; such suturing is difficult. We developed a new, simpler eight-strand suture, which we term the Yoshizu cross-lock. This reduces the numbers of suture passages through the tendons, as well as the numbers of knots.

Visualized procollagen Iα1 demonstrates the intracellular processing of propeptides.

The processing of type I procollagen is essential for fibril formation; however, the steps involved remain controversial. We constructed a live cell imaging system by inserting fluorescent proteins into type I pre-procollagen α1. Based on live imaging and immunostaining, the C-propeptide is intracellularly cleaved at the perinuclear region, including the endoplasmic reticulum, and subsequently accumulates at the upside of the cell.

Flexor tendon repair: recent changes and current methods.

The current clinical methods of flexor tendon repair are remarkably different from those used 20 years ago. This article starts with a review of the current methods, followed by presentation of past experience and current status of six eminent hand surgery units from four continents/regions. Many units are using, or are moving toward using, the recent strong (multi-strand) core suture method together with a simpler peripheral suture.

Wide-Awake Approach for Flexor Digitorum Superficialis Tendon Transfer Followed by Early Active Mobilization.

The standard clinical practice to treat closed ruptures of the flexor digitorum profundus (FDP) tendons includes free tendon grafting; however, it is not suitable when the muscle amplitude of the ruptured FDP is not sufficient. We report outcomes of six patients who underwent flexor digitorum superficialis (FDS) tendon transfer of the ring finger using the wide-awake approach to repair the closed rupture of the FDP tendon of the little finger in zone 3 or 4. The patients were identified by reviewing our institutional billing records from January 2012 to October 2019 for the International Classification of Disease 10 code M66.

Early active mobilization after primary repair of the flexor pollicis longus tendon.

Background: There have been few studies regarding primary flexor tendon repair of the thumb following early active mobilization, whereas there have been multiple such studies of the finger. This study examined the outcomes of patients who underwent early active mobilization after primary repair of the flexor pollicis longus tendon.

Methods: This study was a retrospective case series.

Flexor Tendon Grafting Using Extrasynovial Tendons Followed by Early Active Mobilization.

Purpose: This study evaluated the outcomes of early active mobilization after flexor tendon grafts using extrasynovial tendons with a novel distal fixation technique.

Methods: This study was a retrospective case series. The flexor digitorum profundus (FDP) tendons of 7 digits in 7 patients were reconstructed with extrasynovial tendons, which included the palmaris longs, plantaris, and extensor digitorum longus, in a single- or 2-stage procedure between 2008 and 2017.

Acetaminophen-induced hepatotoxicity of cultured hepatocytes depends on timing of isolation from light-cycle controlled mice.

Most physiological changes follow a daily cycle in animals because their circadian rhythm is adjusted to and synchronized with sunlight. In particular, the circadian rhythm affects liver functions, including pharmacokinetics and metabolism. The influence of circadian rhythm has not been included in hepatotoxicity assays used in drug discovery and development.