Publications by authors named "Koichiro Sudo"
Article Synopsis
- Agyrophilic grains (AGs) are brain lesions that accumulate four-repeat tau and are linked to age-related cognitive decline, but their role in dementia remains uncertain due to conflicting research.
- A study analyzed 30 cases of pure argyrophilic grain disease (pAGD) and 34 control cases to assess the quantity and distribution of Gallyas-positive AGs and associated neuronal loss in various brain regions.
- Results indicated that higher concentrations of AGs in the amygdala and hippocampus significantly correlated with neuronal loss and affected dementia independently of other factors like age and other neurodegenerative stages.
Background: Recent epidemiological studies suggested correlation between gastric cancer (GC) and periodontal disease.
Aims: We aim to clarify involvement of lipopolysaccharide of Porphyromonas gingivalis (Pg.), one of the red complex periodontal pathogens, in the GC development.
Argyrophilic grain disease as a neurodegenerative substrate in late-onset schizophrenia and delusional disorders.
Eur Arch Psychiatry Clin Neurosci
June 2014
To study the relationship between neurodegenerative diseases including argyrophilic grain disease (AGD) and late-onset schizophrenia and delusional disorders (LOSD; onset ≥40 years of age), we pathologically examined 23 patients with LOSD, 71 age-matched normal controls, and 22 psychiatric disease controls (11 depression, six personality disorder, two bipolar disorders, and three neurotic disorders cases). In all LOSD cases (compared to age-matched normal controls), the frequencies of Lewy body disease (LBD), AGD, and corticobasal degeneration (CBD) were 26.1 % (11.
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