A Comparison of Subjective Symptoms of Two Types of Silicone Hydrogel One-Day Disposable Contact Lenses.

Purpose: This study aimed to evaluate the comfort and discomfort of two types of soft contact lenses (SCLs) by comparing their quality of vision, fit, subjective dryness, and handling.

Methods: A total of 62 SCL wearers with contact lens (CL) discomfort were recruited. They were fitted with narafilcon A and verofilcon A for two weeks each by crossover.

Subjective Symptoms of First-Time Wearers of Verofilcon A Silicone Hydrogel One-Day Disposable Contact Lenses: A First Time Use of Verofilcon A (FTVeA) Study.

Purpose Verofilcon A, a new daily disposable silicone hydrogel soft contact lens (SCL), is expected to be more comfortable to wear due to its smooth surface. This study aims to compare the comfort level of verofilcon A with eyeglasses in first-time SCL wearers. Methods A total of 58 new SCL wearers participated in this study.

Comparison of comfort and tear stability with two novel silicone-hydrogel daily disposable contact lenses.

Background: The surface wettability of soft contact lenses (SCLs) affects the wearing comfort. Verofilcon A is a daily disposable silicone hydrogel contact lens with SMARTSURFACE® technology, ensuring high surface wettability.

Purpose: To evaluate tear stability on the surface of verofilcon A and narafilcon A SCLs and correlate these findings with clinical parameters and patients' discomfort.

Patient Satisfaction and Tear Film Break-Up Time After First-Time Wearing of Silicone Hydrogel Contact Lenses.

Purpose: The dryness and discomfort associated with soft contact lenses (SCLs) prevent their continued use. Recently, verofilcon A, a new daily disposable silicone hydrogel material SCL, was introduced, which has a high water content (surface water content of 80% or more) that overcomes the low water content drawback of silicone hydrogels. In this study, we evaluated the non-invasive tear break-up time (NIBUT) and comfort level in individuals wearing verofilcon A SCL for the first time.

Synthesis of linked triple helical DNAs possessing high affinity to triple helical DNA binding protein.

The synthesis of triplexes possessing an anthraquinonyl group and composed of branched oligonucleotides (ONs) is described. Binding ability of a triplex-binding protein (MBP-LOR3(ARF)) to the triplexes was evaluated by an electrophoretic mobility shift assay (EMSA). It was found that the triplex, which has an anthraquinonecarbonyl group at the 5'-end of the third strand and is connected with the pentaerythritol linker, has greater affinity to the protein than an unmodified triplex.